PMID- 10656516
OWN - NLM
STAT- MEDLINE
DCOM- 20000214
LR  - 20190921
IS  - 1388-2457 (Print)
IS  - 1388-2457 (Linking)
VI  - 111
IP  - 1
DP  - 2000 Jan
TI  - The impact of cyclic alternating pattern on heart rate variability during sleep 
      in healthy young adults.
PG  - 99-101
AB  - OBJECTIVE: Cyclic alternating pattern (CAP) consists of arousal-related phasic 
      events while the complementary condition, non-CAP (NCAP), is characterized by a 
      rhythmic background activity, reflecting a condition of stable arousal, during 
      non-REM sleep. The arousal swings that accompany the appearance of CAP on the EEG 
      are associated with transient variations of muscle tone and autonomic activities, 
      including heart rate (HR). The aim of our study was to evaluate HR variability in 
      relation to CAP during non-REM sleep in healthy adults. METHODS: Ten healthy 
      subjects (mean age = 28.1 years) underwent 8 h polysomnography. HR variations 
      were measured by power spectrum analysis. The ECG signals were segmented in 
      correspondence of the different sleep stages and different CAP conditions. 
      RESULTS: A significant difference between CAP and NCAP conditions was found in 
      low frequency (LF) component (increased in CAP) and high frequency (HF) component 
      (decreased in CAP). LF/HF ratio was increased in CAP. CONCLUSION: Physiological 
      fluctuations of the EEG arousal level influence cardiac autonomic activity in 
      normal subjects. The studies on nocturnal variation in sympathetic and vagal tone 
      should take in account the microstructural sleep changes, other than the 
      conventional polysomnographic parameters.
FAU - Ferini-Strambi, L
AU  - Ferini-Strambi L
AD  - Sleep Disorders Center, University of Milano and IRCCS H San Raffaele, Milan, 
      Italy. ferinistrambi.luigi@hsr.it
FAU - Bianchi, A
AU  - Bianchi A
FAU - Zucconi, M
AU  - Zucconi M
FAU - Oldani, A
AU  - Oldani A
FAU - Castronovo, V
AU  - Castronovo V
FAU - Smirne, S
AU  - Smirne S
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Clin Neurophysiol
JT  - Clinical neurophysiology : official journal of the International Federation of 
      Clinical Neurophysiology
JID - 100883319
SB  - IM
MH  - *Activity Cycles
MH  - Adult
MH  - Arousal/physiology
MH  - Electrocardiography
MH  - Electroencephalography
MH  - Female
MH  - Heart Rate/*physiology
MH  - Humans
MH  - Male
MH  - Reference Values
MH  - Sleep/*physiology
MH  - Sleep Stages/physiology
EDAT- 2000/02/03 09:00
MHDA- 2000/02/19 09:00
CRDT- 2000/02/03 09:00
PHST- 2000/02/03 09:00 [pubmed]
PHST- 2000/02/19 09:00 [medline]
PHST- 2000/02/03 09:00 [entrez]
AID - S1388-2457(99)00212-6 [pii]
AID - 10.1016/s1388-2457(99)00212-6 [doi]
PST - ppublish
SO  - Clin Neurophysiol. 2000 Jan;111(1):99-101. doi: 10.1016/s1388-2457(99)00212-6.