PMID- 10658039 OWN - NLM STAT- MEDLINE DCOM- 20000303 LR - 20171213 IS - 8750-7587 (Print) IS - 0161-7567 (Linking) VI - 88 IP - 2 DP - 2000 Feb TI - Effect of menstrual cycle phase on carbohydrate supplementation during prolonged exercise to fatigue. PG - 690-7 AB - The effects of menstrual cycle phase and carbohydrate (CHO) supplementation were investigated during prolonged exercise. Nine healthy, moderately trained women cycled at 70% peak O(2) consumption until exhaustion. Two trials were completed during the follicular (Fol) and luteal (Lut) phases of the menstrual cycle. Subjects consumed 0.6 g CHO. kg body wt(-1). h(-1) (5 ml/kg of a 6% CHO solution every 30 min beginning at min 30 of exercise) or a placebo drink (Pl) during exercise. Time to exhaustion during CHO increased from Pl values (P < 0.05) by 14.4 +/- 8.5 (Fol) and 11.4 +/- 7.1% (Lut); no differences were observed between menstrual cycle phases. CHO attenuated (P < 0.05) the decrease in plasma glucose and insulin and the increase in plasma free fatty acids, tryptophan, epinephrine, and cortisol observed during Pl for both phases. Plasma alanine, glutamine, proline, and isoleucine were lower (P < 0.05) in Lut than in Fol phase. CHO resulted in lower (P < 0.05) plasma tyrosine, valine, leucine, isoleucine, and phenylalanine. These results indicate that the menstrual cycle phase does not alter the effects of CHO supplementation on performance and plasma levels of related substrates during prolonged exercise. FAU - Bailey, S P AU - Bailey SP AD - Department of Physical Therapy Education, Elon College, Elon College, North Carolina 27244, USA. baileys@elon.edu FAU - Zacher, C M AU - Zacher CM FAU - Mittleman, K D AU - Mittleman KD LA - eng PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - J Appl Physiol (1985) JT - Journal of applied physiology (Bethesda, Md. : 1985) JID - 8502536 RN - 0 (Amino Acids) RN - 0 (Dietary Carbohydrates) RN - 0 (Fatty Acids, Nonesterified) RN - 0 (Insulin) RN - WI4X0X7BPJ (Hydrocortisone) RN - X4W3ENH1CV (Norepinephrine) RN - YKH834O4BH (Epinephrine) SB - IM MH - Adult MH - Amino Acids/blood MH - Blood Pressure/drug effects MH - Dietary Carbohydrates/*administration & dosage MH - Dietary Supplements MH - Epinephrine/blood MH - Exercise/*physiology MH - Fatigue/*physiopathology/psychology MH - Fatty Acids, Nonesterified/blood MH - Female MH - Heart Rate/drug effects MH - Humans MH - Hydrocortisone/blood MH - Insulin/blood MH - Menstrual Cycle/*physiology MH - Norepinephrine/blood MH - Oxygen Consumption/drug effects/physiology MH - Pulmonary Gas Exchange/drug effects EDAT- 2000/02/05 09:00 MHDA- 2000/03/11 09:00 CRDT- 2000/02/05 09:00 PHST- 2000/02/05 09:00 [pubmed] PHST- 2000/03/11 09:00 [medline] PHST- 2000/02/05 09:00 [entrez] AID - 10.1152/jappl.2000.88.2.690 [doi] PST - ppublish SO - J Appl Physiol (1985). 2000 Feb;88(2):690-7. doi: 10.1152/jappl.2000.88.2.690.