PMID- 10662857
OWN - NLM
STAT- MEDLINE
DCOM- 20000317
LR  - 20190806
IS  - 1040-4651 (Print)
IS  - 1532-298X (Electronic)
IS  - 1040-4651 (Linking)
VI  - 12
IP  - 2
DP  - 2000 Feb
TI  - Genetic interactions between the chlorate-resistant mutant cr 8 8 and the 
      photomorphogenic mutants cop1 and hy5.
PG  - 199-210
AB  - The chlorate-resistant mutant cr88 is defective in photomorphogenesis, as shown 
      by the phenotypes of long hypocotyls in red light and yellow cotyledons under all 
      light conditions. A subset of light-regulated genes is expressed at subnormal 
      levels in cr88. To analyze further the role that CR88 plays in 
      photomorphogenesis, we investigated the genetic interactions between cr88 and 
      mutants of two other loci affecting photomorphogenesis, CONSTITUTIVE 
      PHOTOMORPHOGENIC1 (COP1) and LONG HYPOCOTYL5 (HY5). COP1 represses the expression 
      of light-regulated genes in the dark, and HY5 inhibits hypocotyl elongation in 
      the light. Using morphological, cellular, and gene expression criteria for 
      epistasis analyses to position CR88 in the genetic hierarchy of the 
      photomorphogenesis pathway, we determined that CR88 acts downstream of COP1 but 
      in a branch separate from HY5. In the course of our analysis, we discovered that 
      light causes extensive destruction of plastids in dark-grown cop1 seedlings and 
      that cr88 prevents this destruction.
FAU - Cao, D
AU  - Cao D
AD  - Department of Biological Sciences, University of Iowa, Iowa City, Iowa 52242, 
      USA.
FAU - Lin, Y
AU  - Lin Y
FAU - Cheng, C L
AU  - Cheng CL
LA  - eng
PT  - Journal Article
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PL  - England
TA  - Plant Cell
JT  - The Plant cell
JID - 9208688
RN  - 0 (Arabidopsis Proteins)
RN  - 0 (Basic-Leucine Zipper Transcription Factors)
RN  - 0 (Carrier Proteins)
RN  - 0 (Chlorates)
RN  - 0 (HY5 protein, Arabidopsis)
RN  - 0 (Nuclear Proteins)
RN  - 0 (Plant Proteins)
RN  - 0 (RNA, Plant)
RN  - EC 2.3.2.27 (AT2G32950 protein, Arabidopsis)
RN  - EC 2.3.2.27 (Ubiquitin-Protein Ligases)
SB  - IM
MH  - *Arabidopsis Proteins
MH  - Basic-Leucine Zipper Transcription Factors
MH  - Carrier Proteins/*genetics
MH  - Chlorates/*pharmacology
MH  - Chromosome Mapping
MH  - Cotyledon/drug effects/*genetics/radiation effects
MH  - *Light
MH  - *Mutation
MH  - Nuclear Proteins/*genetics
MH  - Photosynthesis/genetics
MH  - Plant Proteins/*genetics
MH  - RNA, Plant/genetics
MH  - *Ubiquitin-Protein Ligases
PMC - PMC139758
EDAT- 2000/02/09 09:00
MHDA- 2000/03/25 09:00
PMCR- 2001/02/01
CRDT- 2000/02/09 09:00
PHST- 2000/02/09 09:00 [pubmed]
PHST- 2000/03/25 09:00 [medline]
PHST- 2000/02/09 09:00 [entrez]
PHST- 2001/02/01 00:00 [pmc-release]
AID - 99-0319 [pii]
AID - 10.1105/tpc.12.2.199 [doi]
PST - ppublish
SO  - Plant Cell. 2000 Feb;12(2):199-210. doi: 10.1105/tpc.12.2.199.