PMID- 10674843
OWN - NLM
STAT- MEDLINE
DCOM- 20000301
LR  - 20190516
IS  - 0918-2918 (Print)
IS  - 0918-2918 (Linking)
VI  - 39
IP  - 1
DP  - 2000 Jan
TI  - Chromogranin A expression in hepatocellular carcinoma in a patient with germline 
      MEN1 gene mutation.
PG  - 20-4
AB  - Hepatocellular carcinoma (HCC) was found in a patient with multiple endocrine 
      neoplasia type 1 (MEN 1). The intriguing finding was that the HCC in the patient 
      was positively stained for chromogranin A (CgA), a cellular marker for endocrine 
      and neuroendocrine tumors. The patient had a pancreas endocrine tumor and type C 
      hepatitis, that made pathological diagnosis of the origin of the tumor 
      complicated.
FAU - Nakajima, K
AU  - Nakajima K
AD  - Department of Aging Medicine and Geriatrics, Shinshu University School of 
      Medicine, Matsumoto.
FAU - Sakurai, A
AU  - Sakurai A
FAU - Katai, M
AU  - Katai M
FAU - Yajima, H
AU  - Yajima H
FAU - Mori, J
AU  - Mori J
FAU - Katakura, M
AU  - Katakura M
FAU - Tsuchiya, S
AU  - Tsuchiya S
FAU - Hashizume, K
AU  - Hashizume K
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Japan
TA  - Intern Med
JT  - Internal medicine (Tokyo, Japan)
JID - 9204241
RN  - 0 (CHGA protein, human)
RN  - 0 (Chromogranin A)
RN  - 0 (Chromogranins)
SB  - IM
MH  - Carcinoma, Hepatocellular/chemistry/*complications
MH  - Chromogranin A
MH  - Chromogranins/*analysis
MH  - Fatal Outcome
MH  - Germ-Line Mutation
MH  - Glucagonoma/chemistry
MH  - Hepatitis C/complications
MH  - Humans
MH  - Liver/chemistry
MH  - Liver Neoplasms/chemistry/*complications
MH  - Male
MH  - Middle Aged
MH  - Multiple Endocrine Neoplasia Type 1/*complications/genetics
MH  - Neoplasms, Multiple Primary/chemistry
MH  - Pancreas/chemistry
MH  - Pancreatic Neoplasms/chemistry
EDAT- 2000/02/16 09:00
MHDA- 2000/03/04 09:00
CRDT- 2000/02/16 09:00
PHST- 2000/02/16 09:00 [pubmed]
PHST- 2000/03/04 09:00 [medline]
PHST- 2000/02/16 09:00 [entrez]
AID - 10.2169/internalmedicine.39.20 [doi]
PST - ppublish
SO  - Intern Med. 2000 Jan;39(1):20-4. doi: 10.2169/internalmedicine.39.20.