PMID- 10687731
OWN - NLM
STAT- MEDLINE
DCOM- 20000316
LR  - 20190921
IS  - 1040-8746 (Print)
IS  - 1040-8746 (Linking)
VI  - 12
IP  - 1
DP  - 2000 Jan
TI  - Cytogenetics and cancer.
PG  - 62-7
AB  - Techniques based on fluorescence in situ hybridization (FISH) have bridged the 
      gap between molecular genetics and conventional cytogenetics. Since its 
      introduction in the late 1980s, advanced FISH-based methods have greatly enhanced 
      the cytogenetic analysis of hematopoietic and solid tumors and are rapidly 
      gaining ground in clinical cytogenetic diagnostics. As interest in FISH 
      technologies has grown, it has inspired an era of new FISH-based technologies 
      such as multiplex FISH, spectral karyotyping, and comparative genomic 
      hybridization. In this review, the focus is on the impact of these technologies 
      in the field of cancer genetics.
FAU - Patel, A S
AU  - Patel AS
AD  - Department of Pathology, The Johns Hopkins University School of Medicine, 
      Baltimore, Maryland 21287, USA.
FAU - Hawkins, A L
AU  - Hawkins AL
FAU - Griffin, C A
AU  - Griffin CA
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Curr Opin Oncol
JT  - Current opinion in oncology
JID - 9007265
SB  - IM
MH  - Chromosome Aberrations/diagnosis
MH  - Chromosome Disorders
MH  - Cytogenetics/trends
MH  - Humans
MH  - In Situ Hybridization, Fluorescence/*methods
MH  - Karyotyping/methods
MH  - Neoplasms/*genetics
RF  - 37
EDAT- 2000/02/25 09:00
MHDA- 2000/03/18 09:00
CRDT- 2000/02/25 09:00
PHST- 2000/02/25 09:00 [pubmed]
PHST- 2000/03/18 09:00 [medline]
PHST- 2000/02/25 09:00 [entrez]
AID - 10.1097/00001622-200001000-00011 [doi]
PST - ppublish
SO  - Curr Opin Oncol. 2000 Jan;12(1):62-7. doi: 10.1097/00001622-200001000-00011.