PMID- 10689572
OWN - NLM
STAT- MEDLINE
DCOM- 20000313
LR  - 20191210
IS  - 0379-0738 (Print)
IS  - 0379-0738 (Linking)
VI  - 107
IP  - 1-3
DP  - 2000 Jan 10
TI  - The use of supercritical fluid extraction for the determination of amphetamines 
      in hair.
PG  - 191-9
AB  - A laboratory study interested in the analysis of human hair for drugs-of-abuse 
      was conducted to determine if drugs could be detected and quantified from hair. 
      Supercritical fluid extraction (SFE) techniques followed by GC-MS analysis were 
      applied to extract amphetamines from hair. The group of amphetamines included 
      methylenedioxyamphetamine (MDA), methylenedioxymetamphetamine (MDMA), 
      methylenedioxyethylamphetamine (MDEA) and internal standard mephentermine (MP). 
      To validate information on amphetamine use in hair, powdered hair samples free 
      from drugs were collected and soaked in a known amphetamine standard solution. 
      Authentic fortified case hair samples taken from known drug users known to have 
      consumed amphetamines were also analyzed for amphetamine. Results from this study 
      show that amphetamine use can be detected in spiked and authentic fortified human 
      hair using SFE techniques for qualitative and quantitative reproducible results.
FAU - Allen, D L
AU  - Allen DL
AD  - Department of Forensic Medicine and Science, University of Glasgow, Scotland, UK.
FAU - Oliver, J S
AU  - Oliver JS
LA  - eng
PT  - Journal Article
PL  - Ireland
TA  - Forensic Sci Int
JT  - Forensic science international
JID - 7902034
RN  - 0 (Amphetamines)
RN  - 0 (Designer Drugs)
RN  - 0 (Illicit Drugs)
RN  - 4764-17-4 (3,4-Methylenedioxyamphetamine)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
RN  - ML1I4KK67B (3,4-methylenedioxyethamphetamine)
SB  - IM
MH  - 3,4-Methylenedioxyamphetamine/analogs & derivatives/analysis
MH  - Amphetamines/*analysis/isolation & purification
MH  - Designer Drugs/analysis
MH  - Gas Chromatography-Mass Spectrometry/methods
MH  - Hair/*chemistry
MH  - Humans
MH  - Illicit Drugs/*analysis
MH  - N-Methyl-3,4-methylenedioxyamphetamine/analysis
MH  - Reference Values
MH  - Reproducibility of Results
MH  - Substance Abuse Detection/*methods
MH  - Substance-Related Disorders/diagnosis
EDAT- 2000/02/26 09:00
MHDA- 2000/03/18 09:00
CRDT- 2000/02/26 09:00
PHST- 2000/02/26 09:00 [pubmed]
PHST- 2000/03/18 09:00 [medline]
PHST- 2000/02/26 09:00 [entrez]
AID - S0379-0738(99)00163-2 [pii]
AID - 10.1016/s0379-0738(99)00163-2 [doi]
PST - ppublish
SO  - Forensic Sci Int. 2000 Jan 10;107(1-3):191-9. doi: 10.1016/s0379-0738(99)00163-2.