PMID- 10690576
OWN - NLM
STAT- MEDLINE
DCOM- 20000317
LR  - 20061115
IS  - 1091-4269 (Print)
IS  - 1091-4269 (Linking)
VI  - 10
IP  - 4
DP  - 1999
TI  - Factors differentiating personality-disordered individuals with and without a 
      history of unipolar mood disorder.
PG  - 147-57
AB  - The relationship between mood disorders and personality disorders has been of 
      longstanding interest to clinicians. Despite theoretical reasons to do so, 
      virtually no studies have examined factors that discriminate 
      personality-disordered subjects with a history of mood disorder (PD/HMD) from 
      personality-disordered subjects without a history of mood disorder (PD). This 
      study examined demographic variables, patterns of comorbidity, measures of life 
      functioning, personality traits, and early life experiences differentiating 
      PD/HMD (n = 83) from PD (n = 214). Diagnoses were assigned using structured 
      clinical interviews and a best-estimate procedure. The results suggest that 
      subjects with borderline personality disorder are more likely to have a life 
      history of mood disorder than are subjects with other personality disorders. In 
      addition, PD/HMDs are more likely to receive a diagnosis of anxiety disorder or 
      alcoholism, to have lower Global Assessment of Functioning (GAF) scores, and to 
      have sought treatment than PDs. On self-report measures of personality, PD/HMDs 
      endorse higher levels of trait anxiety and affective lability (e.g., Harm 
      Avoidance, Neuroticism) than do PDs. PD/HMDs are also more likely to report 
      childhood physical and emotional abuse than are PDs, and to describe their 
      parents as using affectionless control. No differences were found between Axis II 
      clusters as a function of mood disorder history. The discussion suggests a 
      potential model in which early environmental stress interacts with constitutional 
      vulnerabilities to put individuals at an increased risk for both mood and anxiety 
      disorders as well as personality disorders.
FAU - Bunce, S C
AU  - Bunce SC
AD  - Department of Psychiatry, MCP Hahnemann School of Medicine, MCP Hahnemann 
      University, Philadelphia, Pennsylvania 19129-4102, USA. SCOTT.BUNCE@drexel.edu
FAU - Coccaro, E
AU  - Coccaro E
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Depress Anxiety
JT  - Depression and anxiety
JID - 9708816
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Affect/physiology
MH  - Aged
MH  - Anxiety Disorders/diagnosis
MH  - Depressive Disorder/complications/*diagnosis
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Personality Disorders/complications/*diagnosis
MH  - Personality Inventory
MH  - Severity of Illness Index
EDAT- 2000/02/26 09:00
MHDA- 2000/03/25 09:00
CRDT- 2000/02/26 09:00
PHST- 2000/02/26 09:00 [pubmed]
PHST- 2000/03/25 09:00 [medline]
PHST- 2000/02/26 09:00 [entrez]
AID - 10.1002/(SICI)1520-6394(1999)10:4<147::AID-DA3>3.0.CO;2-I [pii]
PST - ppublish
SO  - Depress Anxiety. 1999;10(4):147-57.