PMID- 10699418
OWN - NLM
STAT- MEDLINE
DCOM- 20000504
LR  - 20190921
IS  - 1388-2457 (Print)
IS  - 1388-2457 (Linking)
VI  - 111
IP  - 3
DP  - 2000 Mar
TI  - The individual replicability of mismatch negativity at short and long 
      inter-stimulus intervals.
PG  - 546-51
AB  - OBJECTIVES: The individual replicability of the mismatch negativity (MMN) 
      event-related brain potential (ERP) was studied at two different inter-stimulus 
      intervals (ISIs), to establish its potential value for routine clinical 
      evaluation of sound discrimination and auditory sensory memory. METHODS: Ten 
      healthy young subjects were presented sequences of 3 stimulus trains, in two 
      recording sessions approximately 1 month apart. The stimuli in the trains were 
      delivered at an ISI of 300 ms, whereas the inter-train intervals (ITIs) were 0.4 
      s and 4.0 s in different blocks. ERPs were averaged to standard (75 ms) and 
      deviant (25 ms) tones started equiprobably the stimulus trains. RESULTS: 
      Significant Pearson product-moment correlations coefficients were found between 
      sessions at all scalp locations for the short ITI, when the MMN was quantified as 
      the mean amplitude in the 100-200 ms latency window around its peak. However, 
      none of the correlations reached significance for the longer ITI. CONCLUSIONS: 
      MMN appears to be a reliable measure for single-case assessment and follow-ups 
      when obtained at short ISIs and quantified as an integrated window of 
      neuroelectric activation over a temporal span.
FAU - Escera, C
AU  - Escera C
AD  - Neurodynamics Laboratory, Department of Psychiatry and Clinical Psychobiology, 
      University of Barcelona, P. Vall d'Hebron 171, 08035 Barcelona, Catalonia, Spain. 
      cescera@psi.ub.es
FAU - Yago, E
AU  - Yago E
FAU - Polo, M D
AU  - Polo MD
FAU - Grau, C
AU  - Grau C
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Clin Neurophysiol
JT  - Clinical neurophysiology : official journal of the International Federation of 
      Clinical Neurophysiology
JID - 100883319
SB  - IM
MH  - Acoustic Stimulation
MH  - Adult
MH  - Analysis of Variance
MH  - Brain/*physiology
MH  - Electroencephalography
MH  - Evoked Potentials, Auditory/*physiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Time Factors
EDAT- 2000/03/04 09:00
MHDA- 2000/05/08 09:00
CRDT- 2000/03/04 09:00
PHST- 2000/03/04 09:00 [pubmed]
PHST- 2000/05/08 09:00 [medline]
PHST- 2000/03/04 09:00 [entrez]
AID - S1388-2457(99)00274-6 [pii]
AID - 10.1016/s1388-2457(99)00274-6 [doi]
PST - ppublish
SO  - Clin Neurophysiol. 2000 Mar;111(3):546-51. doi: 10.1016/s1388-2457(99)00274-6.