PMID- 10717660
OWN - NLM
STAT- MEDLINE
DCOM- 20000503
LR  - 20091216
IS  - 0951-4198 (Print)
IS  - 0951-4198 (Linking)
VI  - 14
IP  - 6
DP  - 2000
TI  - Qualitative and quantitative end-group analysis of a small molecular weight 
      polyester by matrix-assisted laser desorption/ionization time-of-flight mass 
      spectrometry.
PG  - 482-95
AB  - Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass 
      spectrometry was used for qualitative and quantitative end-group analysis of a 
      small molecular weight polyester, poly(2-butyl-2-ethyl-1,3-propylene phthalate). 
      The presence of carboxyl-terminated linear and cyclic polyester oligomers was 
      confirmed with the help of simple sample preparation methods. The presence of 
      carboxyl end-groups in the polyester chains was verified through their formation 
      of carboxylate salts with alkali metal cations. Cyclic oligomers were identified 
      through deuterium exchange of the exchangeable protons of the polyester. Various 
      inorganic salts were tested for salt formation of the carboxyl end-groups, but 
      only the alkali metal salts proved effective. The influence of the alkali metal 
      salts on the results of the quantitative end-group analysis was also studied. The 
      relative amounts of differently terminated and cyclic oligomers were calculated 
      when the alkali metal salts were used with different matrices. The results showed 
      that both the salts and the matrices used in sample preparation can have a marked 
      effect on the quantitative results of the end-group analysis. The measurements 
      were carried out using 2,5-dihydroxybenzoic acid (DHB), 1,8, 
      9-trihydroxyanthracene (dithranol), and 2-(4-hydroxyphenylazo)benzoic acid (HABA) 
      as matrix compounds. Dithranol and HABA repeatably exhibited similar results, and 
      these results differed from those obtained with DHB probably because of the 
      different ionization mechanisms in the MALDI process.
CI  - Copyright 2000 John Wiley & Sons, Ltd.
FAU - Laine, O
AU  - Laine O
AD  - University of Joensuu, Department of Chemistry, P.O. Box 111, 80101 Joensuu, 
      Finland.
FAU - Osterholm, H
AU  - Osterholm H
FAU - Jarvinen, H
AU  - Jarvinen H
FAU - Wickstrom, K
AU  - Wickstrom K
FAU - Vainiotalo, P
AU  - Vainiotalo P
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Rapid Commun Mass Spectrom
JT  - Rapid communications in mass spectrometry : RCM
JID - 8802365
RN  - 0 (Carboxylic Acids)
RN  - 0 (Indicators and Reagents)
RN  - 0 (Polyesters)
SB  - IM
MH  - Carboxylic Acids/analysis
MH  - Indicators and Reagents
MH  - Molecular Weight
MH  - Polyesters/*analysis
MH  - Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
EDAT- 2000/03/16 09:00
MHDA- 2000/05/08 09:00
CRDT- 2000/03/16 09:00
PHST- 2000/03/16 09:00 [pubmed]
PHST- 2000/05/08 09:00 [medline]
PHST- 2000/03/16 09:00 [entrez]
AID - 10.1002/(SICI)1097-0231(20000331)14:6<482::AID-RCM900>3.0.CO;2-A [pii]
AID - 10.1002/(SICI)1097-0231(20000331)14:6<482::AID-RCM900>3.0.CO;2-A [doi]
PST - ppublish
SO  - Rapid Commun Mass Spectrom. 2000;14(6):482-95. doi: 
      10.1002/(SICI)1097-0231(20000331)14:6<482::AID-RCM900>3.0.CO;2-A.