PMID- 10720719 OWN - NLM STAT- MEDLINE DCOM- 20000504 LR - 20190819 IS - 0378-4274 (Print) IS - 0378-4274 (Linking) VI - 112-113 DP - 2000 Mar 15 TI - Ecotoxicological risk assessment of environmental pollutants in the Arctic. PG - 111-8 AB - Concentrations of such persistent organic pollutants (POPs) as polychlorinated biphenyls (PCBs) are high in certain Arctic animal species. The polar bear, Arctic fox, and glaucous gull may be exposed to PCB levels above lowest-observed-adverse-effect-level (LOAEL) values for adverse effects on reproduction in mammals and birds. However, the dioxin-like congeners seem to be major contributors to the reproductive effects of PCBs and the relative concentrations of these congeners are low in polar bears. Temporal trends for POPs in Arctic wildlife and the sensitivities of Arctic species to these compounds determine the risk for future adverse health effects. FAU - Brunstrom, B AU - Brunstrom B AD - Department of Environmental Toxicology, Uppsala University, Norbyvagen 18A, SE-752 36, Uppsala, Sweden. bjorn.brunstrom@etox.uu.se FAU - Halldin, K AU - Halldin K LA - eng PT - Journal Article PT - Review PL - Netherlands TA - Toxicol Lett JT - Toxicology letters JID - 7709027 RN - 0 (Environmental Pollutants) RN - DFC2HB4I0K (Polychlorinated Biphenyls) SB - IM MH - Animals MH - *Animals, Wild MH - Arctic Regions MH - Environmental Pollutants/isolation & purification/*toxicity MH - No-Observed-Adverse-Effect Level MH - Polychlorinated Biphenyls/isolation & purification/*toxicity MH - Reproduction/*drug effects MH - Risk Assessment RF - 41 EDAT- 2000/03/18 09:00 MHDA- 2000/05/08 09:00 CRDT- 2000/03/18 09:00 PHST- 2000/03/18 09:00 [pubmed] PHST- 2000/05/08 09:00 [medline] PHST- 2000/03/18 09:00 [entrez] AID - S0378427499002015 [pii] AID - 10.1016/s0378-4274(99)00201-5 [doi] PST - ppublish SO - Toxicol Lett. 2000 Mar 15;112-113:111-8. doi: 10.1016/s0378-4274(99)00201-5.