PMID- 10721016
OWN - NLM
STAT- MEDLINE
DCOM- 20000420
LR  - 20191103
IS  - 1057-9230 (Print)
IS  - 1057-9230 (Linking)
VI  - 9
IP  - 2
DP  - 2000 Mar
TI  - Establishing health state valuations for disease specific states: an example from 
      heart disease.
PG  - 149-58
AB  - This study considers the feasibility of defining a QALY from disease-specific 
      data using the New York Heart Association (NYHA) classification of heart failure. 
      The study derives health state values for the four different NYHA classifications 
      of disease progression using the time trade-off (TTO) instrument associated with 
      the five dimensional (EQ-5D) health state valuation method. Consistent mappings 
      between the disease classification and the chosen QALY instrument are found. With 
      this being the case, the assumption of constant proportionality, which is 
      necessary to define the QALY as an acceptable measure of health related 
      preferences, is considered. It is found that constant proportionality does not 
      hold across the more severe health states, thus questioning the use of QALYs as 
      representing cardinal preference structures.
CI  - Copyright 2000 John Wiley & Sons, Ltd.
FAU - Kirsch, J
AU  - Kirsch J
AD  - SmithKline Beecham Limited, Mundells, Welwyn Garden City, UK.
FAU - McGuire, A
AU  - McGuire A
LA  - eng
PT  - Journal Article
PL  - England
TA  - Health Econ
JT  - Health economics
JID - 9306780
SB  - IM
MH  - Adult
MH  - Aged
MH  - Cost-Benefit Analysis/statistics & numerical data
MH  - Female
MH  - *Health Status Indicators
MH  - Heart Diseases/*physiopathology
MH  - Humans
MH  - Interviews as Topic
MH  - Male
MH  - Middle Aged
MH  - Quality-Adjusted Life Years
MH  - State Medicine
MH  - United Kingdom
EDAT- 2000/03/18 09:00
MHDA- 2000/04/25 09:00
CRDT- 2000/03/18 09:00
PHST- 2000/03/18 09:00 [pubmed]
PHST- 2000/04/25 09:00 [medline]
PHST- 2000/03/18 09:00 [entrez]
AID - 10.1002/(SICI)1099-1050(200003)9:2<149::AID-HEC501>3.0.CO;2-N [pii]
AID - 10.1002/(sici)1099-1050(200003)9:2<149::aid-hec501>3.0.co;2-n [doi]
PST - ppublish
SO  - Health Econ. 2000 Mar;9(2):149-58. doi: 
      10.1002/(sici)1099-1050(200003)9:2<149::aid-hec501>3.0.co;2-n.