PMID- 10750343
OWN - NLM
STAT- MEDLINE
DCOM- 20000517
LR  - 20161124
IS  - 0022-9717 (Print)
IS  - 0022-9717 (Linking)
VI  - 49 Suppl 1
DP  - 2000 Feb
TI  - Recovery of decreased local cerebral blood flow detected by the xenon/CT CBF 
      method in a patient with eclampsia.
PG  - A71-4
AB  - A 23-year-old woman presented in our hospital with toxemia, underwent cesarean 
      section at about 36 weeks gestation, and became eclamptic in the immediate 
      postpartum period. Following a complex partial seizure a few hours after the 
      cesarean section, the patient experienced drowsiness, then cortical blindness. 
      Cranial computed tomography (CT) performed at about 24 hours after the onset of 
      the seizure showed low density areas in the bilateral occipital lobes. 
      Intravenous magnesium sulfate was given, and the neurological symptoms 
      disappeared within three weeks. Xenon/CT cerebral blood flow (CBF) was measured 
      during the acute and chronic stages of the patient's eclampsia and compared with 
      cranial magnetic resonance imaging (MRI) performed at about the same time. In the 
      acute stage, MRI showed abnormal T2-hyperintensity signals in the head of the 
      left caudate nucleus and in the bilateral occipital lobes, predominantly in the 
      white matter. Xenon/CT CBF measurement showed decreased local cerebral blood flow 
      (LCBF) in the area of the left anterior cerebral artery (ACA), the bilateral 
      posterior cerebral arteries (PCAs), and the watershed areas of the left 
      hemisphere. In the chronic stage, abnormal T2-hyperintensity signals remained in 
      that part of the left occipital lobe where, in the acute stage, a marked decrease 
      in LCBF had been detected. The main mechanism of eclampsia in this patient is 
      thought to be a reactive vasoconstriction against hypertension rather than a 
      vasodilatation.
FAU - Yamaguchi, K
AU  - Yamaguchi K
AD  - Department of Neurology, School of Medicine, Keio University, Tokyo, Japan.
FAU - Fukuuchi, Y
AU  - Fukuuchi Y
FAU - Nogawa, S
AU  - Nogawa S
FAU - Dembo, T
AU  - Dembo T
FAU - Tomita, Y
AU  - Tomita Y
FAU - Tanaka, K
AU  - Tanaka K
LA  - eng
PT  - Case Reports
PT  - Comparative Study
PT  - Journal Article
PL  - Japan
TA  - Keio J Med
JT  - The Keio journal of medicine
JID - 0376354
RN  - 3H3U766W84 (Xenon)
SB  - IM
MH  - Adult
MH  - *Cerebrovascular Circulation
MH  - Female
MH  - Humans
MH  - Magnetic Resonance Angiography
MH  - Pre-Eclampsia/diagnostic imaging/*physiopathology
MH  - Pregnancy
MH  - Tomography, X-Ray Computed/methods
MH  - Xenon
EDAT- 2000/04/06 09:00
MHDA- 2000/05/20 09:00
CRDT- 2000/04/06 09:00
PHST- 2000/04/06 09:00 [pubmed]
PHST- 2000/05/20 09:00 [medline]
PHST- 2000/04/06 09:00 [entrez]
PST - ppublish
SO  - Keio J Med. 2000 Feb;49 Suppl 1:A71-4.