PMID- 10758923 OWN - NLM STAT- MEDLINE DCOM- 20000421 LR - 20220408 IS - 0002-9149 (Print) IS - 0002-9149 (Linking) VI - 85 IP - 7 DP - 2000 Apr 1 TI - Prognostic usefulness of the tricuspid annular plane systolic excursion in patients with congestive heart failure secondary to idiopathic or ischemic dilated cardiomyopathy. PG - 837-42 AB - The prognostic value of ultrasound evaluation of right ventricular (RV) performance in patients with congestive heart failure (CHF) is still a matter of investigation. We studied 140 consecutive patients with chronic CHF and a left ventricular ejection fraction <35%. All patients underwent a complete echocardiographic evaluation that systematically included the measurement of the tricuspid annular plane systolic excursion (TAPSE). During a follow-up period of 24 +/- 14 months, 45 patients died and 7 underwent emergency heart transplantation. At the multivariate survival analysis (Cox regression model) backward stepwise selection identified a prognostic model with 2 parameters: New York Heart Association (NYHA) class III or IV and TAPSE < or =14 mm (p <000). In a subgroup of 97 patients in sinus rhythm in whom mitral inflow Doppler variables could be measured, survival was further analyzed according to a model in which the significant parameters were included in the same order as usually used in routine clinical practice: clinical variables first, left ventricular function data second, mitral Doppler variables third, and indexes of right ventricular (RV) function last. TAPSE < or =14 mm added significant (p <0.03) prognostic information to NYHA class III or IV, left ventricular ejection fraction of <20%, and mitral deceleration time of < 125 ms. In conclusion, in patients with CHF, TAPSE adds significant prognostic information to the NYHA clinical classification, to the echocardiographic evaluation of left ventricular function, and to mitral Doppler variables. Furthermore, the measurement of TAPSE is easy to obtain in all patients, irrespective of heart rate and rhythm. FAU - Ghio, S AU - Ghio S AD - Dipartimento di Cardiologia and Direzione Scientifica, IRCCS Policlinico S Matteo, Pavia, Italy. s.ghio@smatteo.pv.it FAU - Recusani, F AU - Recusani F FAU - Klersy, C AU - Klersy C FAU - Sebastiani, R AU - Sebastiani R FAU - Laudisa, M L AU - Laudisa ML FAU - Campana, C AU - Campana C FAU - Gavazzi, A AU - Gavazzi A FAU - Tavazzi, L AU - Tavazzi L LA - eng PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Am J Cardiol JT - The American journal of cardiology JID - 0207277 SB - IM MH - Cardiac Catheterization MH - Cardiomyopathy, Dilated/*complications/diagnostic imaging/physiopathology MH - *Echocardiography, Doppler MH - Female MH - Heart Failure/*diagnostic imaging/etiology/mortality/physiopathology MH - Heart Ventricles/*diagnostic imaging/physiopathology MH - Humans MH - Male MH - Middle Aged MH - Myocardial Ischemia/*complications/diagnostic imaging/physiopathology MH - Prognosis MH - Reproducibility of Results MH - Retrospective Studies MH - Stroke Volume MH - Survival Rate MH - Tricuspid Valve/*diagnostic imaging/physiopathology MH - Ventricular Function, Right/*physiology EDAT- 2000/04/12 09:00 MHDA- 2000/04/29 09:00 CRDT- 2000/04/12 09:00 PHST- 2000/04/12 09:00 [pubmed] PHST- 2000/04/29 09:00 [medline] PHST- 2000/04/12 09:00 [entrez] AID - S0002914999008772 [pii] AID - 10.1016/s0002-9149(99)00877-2 [doi] PST - ppublish SO - Am J Cardiol. 2000 Apr 1;85(7):837-42. doi: 10.1016/s0002-9149(99)00877-2.