PMID- 10761107
OWN - NLM
STAT- MEDLINE
DCOM- 20000427
LR  - 20190921
IS  - 0016-6707 (Print)
IS  - 0016-6707 (Linking)
VI  - 105
IP  - 3
DP  - 1999
TI  - A sequence similar to bacterial transposable IS elements present in the 5' 
      untranslated region of the bovine butanediol dehydrogenase cDNA.
PG  - 233-8
AB  - A sequence similar to prokaryotic transposable elements was identified in the 
      long 5' untranslated region (5'UTR) of the butanediol dehydrogenase cDNA isolated 
      from a bovine brain lambda gt11 library. Several observations suggested that this 
      sequence could be related to bacterial IS elements: (a) 58% nucleotide sequence 
      identity, (b) 56% amino acid sequence identity, and (c) the presence of inverted 
      terminal repeats. However, nucleotide sequence analyses of the 5'UTR bovine cDNA 
      showed the presence of chain-terminating nucleotide substitutions that would 
      render it incapable of encoding a functional transposase. Finally, it was 
      observed that different vertebrate genomes have sequences related to this 
      putative transposable element.
FAU - Smania, A M
AU  - Smania AM
AD  - Centro de Investigaciones en Quimica Biologica de Cordoba-CONICET, Facultad de 
      Ciencias Quimicas, Universidad Nacional de Cordoba, Argentina. 
      asmania@dqbfcq.uncor.edu
FAU - Saleh, M C
AU  - Saleh MC
FAU - Argarana, C E
AU  - Argarana CE
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Genetica
JT  - Genetica
JID - 0370740
RN  - 0 (5' Untranslated Regions)
RN  - 0 (DNA Transposable Elements)
RN  - 0 (DNA, Complementary)
RN  - EC 1.1.- (Alcohol Oxidoreductases)
RN  - EC 1.1.1.4 (butanediol dehydrogenase)
SB  - IM
MH  - 5' Untranslated Regions/*genetics
MH  - Alcohol Oxidoreductases/*genetics
MH  - Amino Acid Sequence
MH  - Animals
MH  - Bacteria/*genetics
MH  - Base Sequence
MH  - Brain/enzymology
MH  - Cattle
MH  - *DNA Transposable Elements
MH  - DNA, Complementary/*genetics
MH  - Molecular Sequence Data
MH  - Sequence Homology, Nucleic Acid
EDAT- 2000/04/13 09:00
MHDA- 2000/04/29 09:00
CRDT- 2000/04/13 09:00
PHST- 2000/04/13 09:00 [pubmed]
PHST- 2000/04/29 09:00 [medline]
PHST- 2000/04/13 09:00 [entrez]
AID - 10.1023/a:1003817311179 [doi]
PST - ppublish
SO  - Genetica. 1999;105(3):233-8. doi: 10.1023/a:1003817311179.