PMID- 10763779
OWN - NLM
STAT- MEDLINE
DCOM- 20000608
LR  - 20161124
IS  - 0091-4916 (Print)
IS  - 0091-4916 (Linking)
VI  - 28
IP  - 1
DP  - 2000 Mar
TI  - Quantitative gated myocardial SPECT: effect of collimation on left-ventricular 
      ejection fraction.
PG  - 36-40
AB  - OBJECTIVE: Left-ventricular ejection fraction (LVEF) can be computed from gated 
      myocardial perfusion SPECT studies using quantitative algorithms. The purpose of 
      this study was to compare the LVEF obtained using the conventional 
      high-resolution parallel-hole collimator (HRC) to the Cardiofocal collimator 
      (CFC) (Siemens Medical Systems, Hoffman Estates, IL) using a quantitative LVEF 
      program. METHODS: Thirty-four patients (15 men, 19 women; mean age = 62 y) had 
      either treadmill or pharmacological stress testing with 25-30 mCi 99mTc sestamibi 
      injected at peak stress. Conventional gated SPECT imaging was performed 
      approximately 30 min poststress, first with the HRC collimator, then with the 
      CFC, using the same acquisition parameters on a single-head gamma camera. 
      Traditional (TRAD) determination of LVEF using planar gated blood pool and/or 
      cardiac catherization also was obtained for each patient. RESULTS: The 
      correlation in LVEF between the CFC and HRC acquisitions was excellent, r = 0.99. 
      The correlation between CFC and TRAD LVEF was good, r = 0.95, as was the HRC and 
      TRAD correlation, r = 0.97. The mean LVEF value for HRC was slightly less than 
      TRAD (54% vs. 55.4%), while the CFC mean LVEF was higher (62% vs. 55.4%). 
      Although CFC LVEF correlated well with HRC, mean LVEF value using CFC was higher 
      than HRC. CONCLUSION: The choice of collimator may alter the LVEF obtained from 
      gated SPECT perfusion studies.
FAU - Groch, M W
AU  - Groch MW
AD  - Northwestern University School of Medicine, Chicago, Illinois, USA.
FAU - Takamiya, Y
AU  - Takamiya Y
FAU - Groch, P J
AU  - Groch PJ
FAU - Erwin, W D
AU  - Erwin WD
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - J Nucl Med Technol
JT  - Journal of nuclear medicine technology
JID - 0430303
SB  - IM
MH  - Algorithms
MH  - Electrocardiography
MH  - Exercise Test
MH  - Female
MH  - Gamma Cameras
MH  - Heart/*diagnostic imaging
MH  - Humans
MH  - Image Processing, Computer-Assisted
MH  - Male
MH  - Middle Aged
MH  - *Stroke Volume
MH  - *Tomography, Emission-Computed, Single-Photon/instrumentation/methods
MH  - Ventricular Function, Left
EDAT- 2000/04/14 09:00
MHDA- 2000/06/10 09:00
CRDT- 2000/04/14 09:00
PHST- 2000/04/14 09:00 [pubmed]
PHST- 2000/06/10 09:00 [medline]
PHST- 2000/04/14 09:00 [entrez]
PST - ppublish
SO  - J Nucl Med Technol. 2000 Mar;28(1):36-40.