PMID- 10773662 OWN - NLM STAT- MEDLINE DCOM- 20000613 LR - 20211203 IS - 0301-0171 (Print) IS - 0301-0171 (Linking) VI - 88 IP - 1-2 DP - 2000 TI - Mapping of AKT3, encoding a member of the Akt/protein kinase B family, to human and rodent chromosomes by fluorescence in situ hybridization. PG - 38-40 AB - Previously, a rodent cDNA encoding the third member of the Akt/PKB family of serine/threonine kinases was cloned. We have now cloned the human homolog of this cDNA, and we have used this clone to map the AKT3 gene to human chromosome 1q44 by fluorescence in situ hybridization (FISH). We have also mapped the rodent homologs of AKT3 to rat chromosome 13q24-->q26 and mouse chromosome 1H4-6 by FISH. CI - Copyright 2000 S. Karger AG, Basel FAU - Murthy, S S AU - Murthy SS AD - Human Genetics Program, Fox Chase Cancer Center, Philadelphia, PA 19111, USA. FAU - Tosolini, A AU - Tosolini A FAU - Taguchi, T AU - Taguchi T FAU - Testa, J R AU - Testa JR LA - eng GR - CA06927/CA/NCI NIH HHS/United States GR - CA77429/CA/NCI NIH HHS/United States PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, P.H.S. PL - Switzerland TA - Cytogenet Cell Genet JT - Cytogenetics and cell genetics JID - 0367735 RN - 0 (Oncogene Proteins) RN - EC 2.7.11.1 (AKT3 protein, human) RN - EC 2.7.11.1 (Akt3 protein, mouse) RN - EC 2.7.11.1 (Akt3 protein, rat) RN - EC 2.7.11.1 (Protein Serine-Threonine Kinases) RN - EC 2.7.11.1 (Proto-Oncogene Proteins c-akt) SB - IM MH - Animals MH - Chromosomes, Human, Pair 1/*genetics MH - Cloning, Molecular MH - Fibroblasts MH - Humans MH - *In Situ Hybridization, Fluorescence MH - Lymphocytes MH - Mice MH - Multigene Family/*genetics MH - Oncogene Proteins/*genetics MH - *Physical Chromosome Mapping MH - Protein Serine-Threonine Kinases/*genetics MH - Proto-Oncogene Proteins c-akt MH - Rats MH - Sequence Homology, Amino Acid EDAT- 2000/04/25 09:00 MHDA- 2000/06/17 09:00 CRDT- 2000/04/25 09:00 PHST- 2000/04/25 09:00 [pubmed] PHST- 2000/06/17 09:00 [medline] PHST- 2000/04/25 09:00 [entrez] AID - 15481 [pii] AID - 10.1159/000015481 [doi] PST - ppublish SO - Cytogenet Cell Genet. 2000;88(1-2):38-40. doi: 10.1159/000015481.