PMID- 10774967 OWN - NLM STAT- MEDLINE DCOM- 20000620 LR - 20071115 IS - 0013-726X (Print) IS - 0013-726X (Linking) VI - 32 IP - 4 DP - 2000 Apr TI - Changes in cardiopulmonary parameters during upper gastrointestinal endoscopy in patients with heart disease: towards safer endoscopy. PG - 287-93 AB - BACKGROUND AND STUDY AIMS: Gastrointestinal endoscopy is an invasive examination. The aims of this study were to elucidate the effects and risks of upper gastrointestinal endoscopy with regard to cardiopulmonary functions in patients with heart disease, and to establish safety guidelines for use during endoscopy in this particular group of patients. PATIENTS AND METHODS: The patients involved were 53 inpatients in whom upper gastrointestinal endoscopy was carried out before cardiac surgery. Their cardiac functions had been evaluated previously. Electrocardiography with two leads (II, V5) was used, and blood pressure and peripheral oxygen saturation (SpO2) were monitored throughout the procedure. The relationship between the changes in cardiopulmonary parameters during endoscopy and the cardiac functions was analyzed. RESULTS: Heart rate increased immediately after insertion of the endoscope (P < 0.01). There was a significantly higher incidence of ventricular and supraventricular extrasystoles during observation of the second portion of the duodenum (P < 0.05). A lower cardiac index (P < 0.05) and a higher New York Heart Association (NYHA) functional classification (P < 0.05) were found in patients with oxygen desaturation than in patients without it. Two patients with severe coronary artery lesions showed marked ST-T depression, and these ischemic changes were thought to be due to increase in cardiac work during endoscopy. CONCLUSIONS: Upper gastrointestinal endoscopy has many adverse effects on cardiopulmonary functions in patients with heart disease. In our study, the clinical value of very close monitoring and administration of oxygen for patients with heart disease was confirmed by objective data. FAU - Yazawa, K AU - Yazawa K AD - Dept. of Surgery, Shinshu University School of Medicine, Matsumoto, Japan. FAU - Adachi, W AU - Adachi W FAU - Koide, N AU - Koide N FAU - Watanabe, H AU - Watanabe H FAU - Koike, S AU - Koike S FAU - Hanazaki, K AU - Hanazaki K LA - eng PT - Clinical Trial PT - Controlled Clinical Trial PT - Journal Article PL - Germany TA - Endoscopy JT - Endoscopy JID - 0215166 SB - IM MH - Aged MH - Arrhythmias, Cardiac/diagnosis/etiology MH - Blood Pressure Determination MH - Cardiovascular Diseases/*diagnosis/*physiopathology MH - *Electrocardiography MH - Endoscopy, Gastrointestinal/*adverse effects/methods MH - Female MH - Heart Rate/physiology MH - Hemodynamics/*physiology MH - Humans MH - Male MH - Middle Aged MH - Monitoring, Physiologic/methods MH - Oxygen Consumption/physiology MH - Probability MH - Reference Values MH - Risk Assessment MH - Statistics, Nonparametric EDAT- 2000/04/25 09:00 MHDA- 2000/06/24 11:00 CRDT- 2000/04/25 09:00 PHST- 2000/04/25 09:00 [pubmed] PHST- 2000/06/24 11:00 [medline] PHST- 2000/04/25 09:00 [entrez] AID - 10.1055/s-2000-7377 [doi] PST - ppublish SO - Endoscopy. 2000 Apr;32(4):287-93. doi: 10.1055/s-2000-7377.