PMID- 10785284
OWN - NLM
STAT- MEDLINE
DCOM- 20000711
LR  - 20190910
IS  - 0165-1838 (Print)
IS  - 0165-1838 (Linking)
VI  - 80
IP  - 3
DP  - 2000 May 12
TI  - Attenuated cardiovascular adjustment to sustained static exercise after 
      carbohydrate loading.
PG  - 175-82
AB  - We examined whether a higher plasma lactic acid (LA) concentration resulting from 
      carbohydrate (CHO)-loading affects the cardiovascular responses to exercise 
      through a greater activation of LA-induced metaboreflex. Before and after 
      CHO-loading, LA concentration, mean arterial blood pressure (MAP), heart rate 
      (HR), cardiac output (CO), rating perceived exertion (RPE), and integrated 
      electromyogram (iEMG) of the vastus lateralis were studied during a sustained 
      static knee extension of single legs in 16 volunteers. The CHO-loading comprised 
      an exhaustive bout of one-legged cycling (73+/-3% of maximal oxygen uptake for 
      130-160 min) and consuming a low-CHO diet for 2-3 days and a high-CHO diet for 
      the next 3 days. In the leg that performed the exercise (the experimental leg), 
      the LA concentration after CHO-loading was significantly increased, but the 
      magnitude of MAP, HR, and CO responses during static exercise was significantly 
      decreased in parallel with a significant reduction of RPE and iEMG. In the 
      control leg, there were no changes in the variables before and after CHO-loading. 
      These results suggest that the increased LA concentration resulting from 
      CHO-loading did not affect the cardiovascular adjustment to the sustained 
      exercise. Other mechanisms related to the reduction of RPE and iEMG seem to be 
      responsible for the attenuated cardiovascular responses observed in the 
      experimental leg after CHO-loading.
FAU - Sadamoto, T
AU  - Sadamoto T
AD  - Graduate School of Human Culture, Nara's Women's University, Division of 
      Integrated Sciences, Japan. sadamoto@cc.nara-wu.ac.jp
FAU - Kusano, M
AU  - Kusano M
FAU - Yamagiwa, T
AU  - Yamagiwa T
LA  - eng
PT  - Clinical Trial
PT  - Controlled Clinical Trial
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - J Auton Nerv Syst
JT  - Journal of the autonomic nervous system
JID - 8003419
RN  - 0 (Dietary Carbohydrates)
RN  - 33X04XA5AT (Lactic Acid)
SB  - IM
MH  - Adult
MH  - Cardiovascular System/drug effects/*metabolism
MH  - Dietary Carbohydrates/*metabolism/pharmacology
MH  - Electrocardiography
MH  - Electromyography
MH  - Exercise/*physiology
MH  - Exercise Test
MH  - Female
MH  - Hemodynamics/drug effects/physiology
MH  - Humans
MH  - Isometric Contraction/drug effects/*physiology
MH  - Knee/physiology
MH  - Lactic Acid/blood
MH  - Muscle, Skeletal/drug effects/*metabolism
MH  - Physical Exertion/drug effects/physiology
MH  - Vascular Resistance/drug effects/physiology
EDAT- 2000/04/28 09:00
MHDA- 2000/07/15 11:00
CRDT- 2000/04/28 09:00
PHST- 2000/04/28 09:00 [pubmed]
PHST- 2000/07/15 11:00 [medline]
PHST- 2000/04/28 09:00 [entrez]
AID - S0165183800001016 [pii]
AID - 10.1016/s0165-1838(00)00101-6 [doi]
PST - ppublish
SO  - J Auton Nerv Syst. 2000 May 12;80(3):175-82. doi: 10.1016/s0165-1838(00)00101-6.