PMID- 10789712
OWN - NLM
STAT- MEDLINE
DCOM- 20000512
LR  - 20190921
IS  - 0886-0440 (Print)
IS  - 0886-0440 (Linking)
VI  - 14
IP  - 3
DP  - 1999 May-Jun
TI  - Intermediate-term results of partial left ventriculectomy.
PG  - 214-7
AB  - Partial left ventriculectomy (PLV) has been introduced as an option for patients 
      with end-stage dilated cardiomyopathy. We report the result of a prospective 
      trial of PLV in patients with idiopathic dilated cardiomyopathy, left ventricular 
      end-diastolic diameter (LVEDD) > 7 cm, refractory New York Heart Association 
      (NYHA) Class IV symptoms, and depressed exercise oxygen consumption studies. 
      Sixteen patients underwent a PLV with a mean follow-up of 13 months. Fourteen 
      patients were male. Mean age was 49.6+/-10.5 years (range 30 to 67 years). Left 
      ventricular ejection fraction (LVEF) improved after surgery from 13.9+/-5.6 to 
      21.0+/-8.4, and this improvement persisted for up to 12 months after operation. 
      LVEDD and NYHA Class also were significantly improved after surgery and for up to 
      12 months of follow-up. Operative mortality was 6.25%. Twelve-month survival was 
      86% by Kaplan-Meier analysis. Four (25%) of 16 patients that had initial 
      improvement after PLV developed recurrent heart failure and were listed for 
      transplantation. Freedom from need for listing for heart transplantation was 65% 
      at 12 months. Freedom from death or the need for relisting at 12 months was 56%. 
      PLV can be performed with acceptable early and 12-month mortality. Significant 
      improvements in LVEF, LVEDD, and NYHA Class are seen at up to 12 months of 
      follow-up. Some patients will develop recurrent heart failure and require 
      relisting for heart transplantation.
FAU - Dowling, R D
AU  - Dowling RD
AD  - The Department of Surgery, University of Louisville, Kentucky, USA. 
      rddowl01@homer.louisville.edu
FAU - Koenig, S
AU  - Koenig S
FAU - Laureano, M A
AU  - Laureano MA
FAU - Gray, L A
AU  - Gray LA
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Card Surg
JT  - Journal of cardiac surgery
JID - 8908809
SB  - IM
MH  - Adult
MH  - Aged
MH  - Cardiomyopathy, Dilated/mortality/physiopathology/*surgery
MH  - Female
MH  - Heart Ventricles/*surgery
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Papillary Muscles/surgery
MH  - Prospective Studies
MH  - Survival Analysis
MH  - Treatment Outcome
MH  - Ventricular Function, Left
EDAT- 2000/05/02 09:00
MHDA- 2000/05/20 09:00
CRDT- 2000/05/02 09:00
PHST- 2000/05/02 09:00 [pubmed]
PHST- 2000/05/20 09:00 [medline]
PHST- 2000/05/02 09:00 [entrez]
AID - 10.1111/j.1540-8191.1999.tb00982.x [doi]
PST - ppublish
SO  - J Card Surg. 1999 May-Jun;14(3):214-7. doi: 10.1111/j.1540-8191.1999.tb00982.x.