PMID- 10812165
OWN - NLM
STAT- MEDLINE
DCOM- 20000608
LR  - 20190816
IS  - 0165-4608 (Print)
IS  - 0165-4608 (Linking)
VI  - 119
IP  - 1
DP  - 2000 May
TI  - Precise localization by microdissection/reverse ISH and FISH of the 
      t(15;17)(q24;q21.1) chromosomal breakpoints associated with acute promyelocytic 
      leukemia.
PG  - 15-7
AB  - The acute promyelocytic leukemia (APL M3)-associated translocation (15;17) has 
      been described as having breakpoints variably located between 15q22 and 15q26, 
      and 17q11 and 17q25. Most of the recent studies using DNA probes (fluorescence in 
      situ hybridization [FISH]) for analysis have indicated the chromosome 15 
      breakpoint to be in 15q22. We have utilized a combination of G-banding, FISH, and 
      chromosome microdissection/reverse ISH to precisely map the breakpoint to 
      t(15;17)(q24;q21.1).
FAU - Stock, A D
AU  - Stock AD
AD  - Department of Pathology, University of Nevada School of Medicine, Reno, NV 89502, 
      USA.
FAU - Dennis, T R
AU  - Dennis TR
FAU - Spallone, P A
AU  - Spallone PA
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Cancer Genet Cytogenet
JT  - Cancer genetics and cytogenetics
JID - 7909240
SB  - IM
MH  - Chromosome Banding
MH  - Chromosome Fragility
MH  - *Chromosomes, Human, Pair 15
MH  - *Chromosomes, Human, Pair 17
MH  - Humans
MH  - In Situ Hybridization/*methods
MH  - Karyotyping
MH  - Leukemia, Promyelocytic, Acute/*genetics
MH  - *Translocation, Genetic
EDAT- 2000/05/17 09:00
MHDA- 2000/06/10 09:00
CRDT- 2000/05/17 09:00
PHST- 2000/05/17 09:00 [pubmed]
PHST- 2000/06/10 09:00 [medline]
PHST- 2000/05/17 09:00 [entrez]
AID - S0165-4608(99)00207-1 [pii]
AID - 10.1016/s0165-4608(99)00207-1 [doi]
PST - ppublish
SO  - Cancer Genet Cytogenet. 2000 May;119(1):15-7. doi: 10.1016/s0165-4608(99)00207-1.