PMID- 10827414
OWN - NLM
STAT- MEDLINE
DCOM- 20000628
LR  - 20221207
IS  - 0190-9622 (Print)
IS  - 0190-9622 (Linking)
VI  - 42
IP  - 6
DP  - 2000 Jun
TI  - Annular erythema of Sjogren's syndrome in a white woman.
PG  - 1069-72
AB  - Annular erythema of Sjogren's syndrome (AE-SS) is believed to be the Asian 
      counterpart of subacute cutaneous lupus erythematosus (SCLE) in white persons. We 
      report the second case of a white person with AE-SS, diagnosed by clinical and 
      serologic findings, as well as the absence of histologic criteria for SCLE. The 
      diagnosis of AE-SS was established by symptoms of xerophthalmia and xerostomia, 
      as well as by examination of skin and salivary gland biopsy specimens. Evaluation 
      showed the presence of anti-Ro(SS-A) and anti-La(SS-B) autoantibody, with the 
      presence of anti-Ro(SS-A) antibody against the 60-kd, but not the 52-kd, epitope, 
      a pattern frequently seen in both the Asians with AE-SS and in white patients 
      with SCLE. Both skin and sicca symptoms were alleviated with combination 
      antimalarial therapy, which included hydroxychloroquine and quinacrine. This case 
      demonstrates that AE-SS can occur in white patients and that the autoantibody 
      profile is similar to that described in Asians with this disease.
FAU - Haimowitz, J E
AU  - Haimowitz JE
AD  - Department of Dermatology, University of Pennsylvania, Cooper Medical Center, 
      Philadelphia 19104, USA.
FAU - McCauliffe, D P
AU  - McCauliffe DP
FAU - Seykora, J
AU  - Seykora J
FAU - Werth, V P
AU  - Werth VP
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - J Am Acad Dermatol
JT  - Journal of the American Academy of Dermatology
JID - 7907132
RN  - 0 (Autoantibodies)
SB  - IM
MH  - Aged
MH  - Autoantibodies/analysis
MH  - Biopsy
MH  - Diagnosis, Differential
MH  - Erythema/*etiology/immunology
MH  - Female
MH  - Humans
MH  - Salivary Glands/pathology
MH  - Sjogren's Syndrome/*complications
MH  - Skin/pathology
MH  - White People
EDAT- 2000/05/29 09:00
MHDA- 2000/07/06 11:00
CRDT- 2000/05/29 09:00
PHST- 2000/05/29 09:00 [pubmed]
PHST- 2000/07/06 11:00 [medline]
PHST- 2000/05/29 09:00 [entrez]
AID - S0190-9622(00)90305-0 [pii]
PST - ppublish
SO  - J Am Acad Dermatol. 2000 Jun;42(6):1069-72.