PMID- 10834013 OWN - NLM STAT- MEDLINE DCOM- 20000628 LR - 20180217 IS - 0001-5547 (Print) IS - 0001-5547 (Linking) VI - 44 IP - 3 DP - 2000 May-Jun TI - Localized tenosynovial giant cell tumor of tendon sheath. A case report. PG - 463-6 AB - BACKGROUND: Localized tenosynovial giant cell tumor of tendon sheath (TGCT-L) is a benign, slowly growing lesion with a peak incidence in the third to fifth decade of life. It is thought to arise from the synovium of tendon sheaths, frequently affecting interphalangeal joints of the hands, feet, ankles and knees. Although the histopathologic appearances are well established, only a few reports describe the cytomorphology of this lesion. CASE: A 37-year-old female presented with a slowly growing, nontender mass located near the left ankle joint. The cytologic features of localized tenosynovial giant cell tumor of tendon sheath (TGCT-L) include abundant mononuclear histiocytic cells occurring singly and in three-dimensional tissue fragments, hemosiderin within histiocytes and a few multinucleated giant cells. Subsequently, the histopathologic examination of the surgical specimen was proven to be TGCT-L. CONCLUSION: Fine needle aspiration cytology can be used as a diagnostic tool for early and accurate detection of TGCT-L since the cytologic features combined with clinical details are sufficiently distinctive. FAU - Choudhury, M AU - Choudhury M AD - Department of Pathology, Lady Hardinge Medical College, New Delhi, India. FAU - Jain, R AU - Jain R FAU - Nangia, A AU - Nangia A FAU - Logani, K B AU - Logani KB LA - eng PT - Case Reports PT - Journal Article PL - Switzerland TA - Acta Cytol JT - Acta cytologica JID - 0370307 SB - IM MH - Adult MH - Ankle Joint MH - Female MH - Giant Cell Tumors/*pathology MH - Humans MH - Muscle Neoplasms/*pathology MH - Synovial Membrane/pathology MH - Tendons/pathology EDAT- 2000/06/02 09:00 MHDA- 2000/07/06 11:00 CRDT- 2000/06/02 09:00 PHST- 2000/06/02 09:00 [pubmed] PHST- 2000/07/06 11:00 [medline] PHST- 2000/06/02 09:00 [entrez] AID - 10.1159/000328500 [doi] PST - ppublish SO - Acta Cytol. 2000 May-Jun;44(3):463-6. doi: 10.1159/000328500.