PMID- 10834624
OWN - NLM
STAT- MEDLINE
DCOM- 20000926
LR  - 20220317
IS  - 0010-440X (Print)
IS  - 0010-440X (Linking)
VI  - 41
IP  - 3
DP  - 2000 May-Jun
TI  - Insight and outcome in bipolar, unipolar, and anxiety disorders.
PG  - 167-71
AB  - We performed a study to assess the relationship between impairment of insight and 
      the long-term outcome in affective and anxiety disorders. Standardized insight 
      assessments were made using the Scale to Assess Unawareness of Mental Disorder 
      (SUMD) in 101 outpatients with psychiatric disorders, mostly affective and 
      anxiety disorders, treated over 1 year in a university-based clinic. Outcome was 
      prospectively assessed with the Clinical Global Impression (CGI) and Global 
      Assessment of Functioning (GAF) rating scales. The mean follow-up period was 3.9 
      months. Initial impairment of insight did not correlate with poor outcome. 
      However, improvement in insight correlated with good outcome, particularly in 
      bipolar disorder type I (r = .56 to .67, P = .0005). Insight was similarly 
      impaired in bipolar and unipolar major depressive disorders, and more so than in 
      anxiety disorders (P = .002). An association between a lack of improvement in 
      insight and a poor outcome, most significantly in bipolar disorder type I, was 
      observed in this sample. We found a greater relative impairment of insight in 
      mood versus anxiety disorders.
FAU - Ghaemi, S N
AU  - Ghaemi SN
AD  - Harvard Bipolar Research Program, Massachusetts General Hospital, Consolidated 
      Department of Psychiatry, Harvard Medical School, Boston 02114, USA.
FAU - Boiman, E
AU  - Boiman E
FAU - Goodwin, F K
AU  - Goodwin FK
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Compr Psychiatry
JT  - Comprehensive psychiatry
JID - 0372612
SB  - IM
MH  - Adult
MH  - Ambulatory Care
MH  - Anxiety Disorders/*psychology/therapy
MH  - *Awareness
MH  - Bipolar Disorder/*psychology/therapy
MH  - Depressive Disorder, Major/*psychology/therapy
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Personality Assessment
MH  - Psychotic Disorders/*psychology/therapy
MH  - Treatment Outcome
EDAT- 2000/06/02 09:00
MHDA- 2000/09/30 11:01
CRDT- 2000/06/02 09:00
PHST- 2000/06/02 09:00 [pubmed]
PHST- 2000/09/30 11:01 [medline]
PHST- 2000/06/02 09:00 [entrez]
AID - S0010-440X(00)90043-9 [pii]
AID - 10.1016/S0010-440X(00)90043-9 [doi]
PST - ppublish
SO  - Compr Psychiatry. 2000 May-Jun;41(3):167-71. doi: 10.1016/S0010-440X(00)90043-9.