PMID- 10837075 OWN - NLM STAT- MEDLINE DCOM- 20000712 LR - 20240109 IS - 0732-0582 (Print) IS - 0732-0582 (Linking) VI - 18 DP - 2000 TI - Immunobiology of dendritic cells. PG - 767-811 AB - Dendritic cells (DCs) are antigen-presenting cells with a unique ability to induce primary immune responses. DCs capture and transfer information from the outside world to the cells of the adaptive immune system. DCs are not only critical for the induction of primary immune responses, but may also be important for the induction of immunological tolerance, as well as for the regulation of the type of T cell-mediated immune response. Although our understanding of DC biology is still in its infancy, we are now beginning to use DC-based immunotherapy protocols to elicit immunity against cancer and infectious diseases. FAU - Banchereau, J AU - Banchereau J AD - Baylor Institute for Immunology Research, Dallas, Texas 75204, USA. j.banchereau@baylordallas.edu FAU - Briere, F AU - Briere F FAU - Caux, C AU - Caux C FAU - Davoust, J AU - Davoust J FAU - Lebecque, S AU - Lebecque S FAU - Liu, Y J AU - Liu YJ FAU - Pulendran, B AU - Pulendran B FAU - Palucka, K AU - Palucka K LA - eng GR - CA78846A/CA/NCI NIH HHS/United States PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, P.H.S. PT - Review PL - United States TA - Annu Rev Immunol JT - Annual review of immunology JID - 8309206 RN - 0 (Antigens) SB - IM MH - Animals MH - Antigen Presentation/immunology MH - Antigens/immunology MH - B-Lymphocytes/immunology MH - Dendritic Cells/classification/*immunology MH - Humans MH - Lymphocyte Activation/immunology MH - T-Lymphocytes/immunology RF - 289 EDAT- 2000/06/03 09:00 MHDA- 2000/07/15 11:00 CRDT- 2000/06/03 09:00 PHST- 2000/06/03 09:00 [pubmed] PHST- 2000/07/15 11:00 [medline] PHST- 2000/06/03 09:00 [entrez] AID - 18/1/767 [pii] AID - 10.1146/annurev.immunol.18.1.767 [doi] PST - ppublish SO - Annu Rev Immunol. 2000;18:767-811. doi: 10.1146/annurev.immunol.18.1.767.