PMID- 10839481 OWN - NLM STAT- MEDLINE DCOM- 20001002 LR - 20220330 IS - 0937-4477 (Print) IS - 0937-4477 (Linking) VI - 257 IP - 3 DP - 2000 TI - Familial idiopathic facial palsy. PG - 117-9 AB - The etiology of idiopathic facial palsy (IFP) is still not defined. Familial inheritance has been found in 4-14% of cases. Among 116 patients with IFP admitted to the otolaryngology and neurology clinics at Kutahya State Hospital, 12 had positive family histories involving 10 different families. Review of the patients' histories showed that 13 members of families previously had IFP. In all, the 25 patients with familial IFP consisted of 12 males and 13 females and had an average age at onset of 34.3 years. Class I human leukocyte antigen (HLA) was investigated in 11 patients with familial IFP belonging to four separate families. The follow-up period was approximately 2 months. All cases except one recovered completely, with the latter patient having minimal contracture and facial paresis. However, HLA showed no significant increases in class I antigens. No notable difference was found in the clinical courses of patients with familial and non-familial IFP. FAU - Doner, F AU - Doner F AD - Department of Otolaryngology, The Medical School, Suleyman Demirel University, Isparta, Turkey. FAU - Kutluhan, S AU - Kutluhan S LA - eng PT - Journal Article PL - Germany TA - Eur Arch Otorhinolaryngol JT - European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery JID - 9002937 RN - 0 (Histocompatibility Antigens Class I) SB - IM MH - Adult MH - Facial Paralysis/*genetics MH - Female MH - Follow-Up Studies MH - Gene Frequency MH - Histocompatibility Antigens Class I/genetics MH - Humans MH - Male MH - Pedigree EDAT- 2000/06/06 09:00 MHDA- 2000/10/07 11:01 CRDT- 2000/06/06 09:00 PHST- 2000/06/06 09:00 [pubmed] PHST- 2000/10/07 11:01 [medline] PHST- 2000/06/06 09:00 [entrez] AID - 10.1007/s004050050205 [doi] PST - ppublish SO - Eur Arch Otorhinolaryngol. 2000;257(3):117-9. doi: 10.1007/s004050050205.