PMID- 10849291
OWN - NLM
STAT- MEDLINE
DCOM- 20000726
LR  - 20190915
IS  - 0962-1083 (Print)
IS  - 0962-1083 (Linking)
VI  - 9
IP  - 6
DP  - 2000 Jun
TI  - Genetic analysis of a documented population bottleneck: introduced Bennett's 
      wallabies (Macropus rufogriseus rufogriseus) in New Zealand.
PG  - 753-63
AB  - Few bottlenecks of wild populations are sufficiently well-documented to 
      constitute models for testing theories about the impact of bottlenecks on genetic 
      variation, and subsequent population persistence. Relevant details of the 
      Bennett's wallaby (Macropus rufogriseus rufogriseus) introduction into New 
      Zealand were recorded (founder number, source and approximate bottleneck 
      duration) and suggest this may provide a rare opportunity to examine the efficacy 
      of tests designed to detect recent bottlenecks in wild populations. We first 
      assessed the accuracy of historic accounts of the introduction using genetic 
      diversity detected in mitochondrial DNA (mtDNA) and at five microsatellite loci. 
      Phylogenetic analyses of mtDNA D-loop sequence haplotypes were consistent with 
      the reported origin of the founders as Tasmania, rather than one of the Bass 
      Strait islands in which Bennett's wallabies are also found. Microsatellite allele 
      frequencies from the Tasmanian source population were then used to seed 
      bottleneck simulations encompassing varying sizes and numbers of generations, in 
      order to assess the severity of bottleneck consistent with diversity observed in 
      the New Zealand population. The results suggested that the founder number was 
      unlikely to have been as small as the three animals suggested by the account of 
      the introduction. Nonetheless, the bottleneck was probably severe; in the range 
      of three to five pairs of wallabies for one to three generations. It resulted in 
      significantly reduced levels of allelic diversity and heterozygosity relative to 
      the source population. This bottleneck is only detectable under the infinite 
      allele model (IAM) and not under the stepwise mutation model (SMM) or the 
      two-phase model (TPM), and possible explanations for this are discussed.
FAU - Le Page, S L
AU  - Le Page SL
AD  - Department of Biological Sciences, Macquarie University, Sydney, NSW 2109, 
      Australia.
FAU - Livermore, R A
AU  - Livermore RA
FAU - Cooper, D W
AU  - Cooper DW
FAU - Taylor, A C
AU  - Taylor AC
LA  - eng
SI  - GENBANK/AF101287
SI  - GENBANK/AF101288
SI  - GENBANK/AF101289
SI  - GENBANK/AF101290
SI  - GENBANK/AF101291
SI  - GENBANK/AF101292
SI  - GENBANK/AF101293
SI  - GENBANK/AF101294
SI  - GENBANK/AF101295
SI  - GENBANK/AF101296
SI  - GENBANK/AF101297
SI  - GENBANK/AF101298
SI  - GENBANK/AF101299
SI  - GENBANK/AF101300
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Mol Ecol
JT  - Molecular ecology
JID - 9214478
RN  - 0 (DNA, Mitochondrial)
SB  - IM
MH  - Animals
MH  - Australia
MH  - Computer Simulation
MH  - DNA, Mitochondrial/genetics
MH  - Founder Effect
MH  - Genetic Techniques
MH  - Genetic Variation
MH  - *Genetics, Population
MH  - Macropodidae/*genetics
MH  - Microsatellite Repeats
MH  - Models, Genetic
MH  - Molecular Sequence Data
MH  - New Zealand
MH  - *Phylogeny
EDAT- 2000/06/10 09:00
MHDA- 2000/08/01 11:00
CRDT- 2000/06/10 09:00
PHST- 2000/06/10 09:00 [pubmed]
PHST- 2000/08/01 11:00 [medline]
PHST- 2000/06/10 09:00 [entrez]
AID - mec922 [pii]
AID - 10.1046/j.1365-294x.2000.00922.x [doi]
PST - ppublish
SO  - Mol Ecol. 2000 Jun;9(6):753-63. doi: 10.1046/j.1365-294x.2000.00922.x.