PMID- 10862122
OWN - NLM
STAT- Publisher
LR  - 20191120
IS  - 1096-9888 (Electronic)
IS  - 1076-5174 (Linking)
VI  - 35
IP  - 6
DP  - 2000 Jun
TI  - Regioisomeric differentiation of 2,3- and 3,4-methylenedioxy ring-substituted 
      phenylalkylamines by gas chromatography/tandem mass spectrometry.
PG  - 705-10
AB  - Numerous abused drugs of the 3,4-methylenedioxymetamphetamine (MDMA; Ecstasy; 
      N-methyl-1-(3,4-methylenedioxyphenyl)-2-propaneamine) type and various alkyl 
      chain- and aromatic ring-substituted isomers give very similar electron 
      ionization (EI) mass spectra. This seriously affects the analysis of especially 
      ring regioisomeric drug variants. Using collision-induced dissociation (CID) 
      (argon) under EI and chemical ionization, the mass spectra of 18 2,3- and 3, 
      4-methylenedioxy ring-substituted phenylethylamines were recorded. These 
      techniques permitted an unequivocal differentiation of all studied ring 
      regioisomeric methylenedioxyphenylethylamines. CID mass spectrometry therefore 
      appear to be a reliable tool to establish the kind of ring substitution pattern 
      in regioisomeric methylenedioxyphenalkylamines. Copyright 2000 John Wiley & Sons, 
      Ltd.
FAU - Borth, S
AU  - Borth S
AD  - Pharmazeutisches Institut, Christian Albrechts Universitat Kiel, Gutenbergstrasse 
      76, D-24118 Kiel, Germany.
FAU - Hansel, W
AU  - Hansel W
FAU - Rosner, P
AU  - Rosner P
FAU - Junge, T
AU  - Junge T
LA  - eng
PT  - Journal Article
PL  - England
TA  - J Mass Spectrom
JT  - Journal of mass spectrometry : JMS
JID - 9504818
EDAT- 2000/06/22 00:00
MHDA- 2000/06/22 00:00
CRDT- 2000/06/22 00:00
PHST- 2000/06/22 00:00 [pubmed]
PHST- 2000/06/22 00:00 [medline]
PHST- 2000/06/22 00:00 [entrez]
AID - 10.1002/1096-9888(200006)35:6<705::AID-JMS997>3.0.CO;2-3 [pii]
AID - 10.1002/1096-9888(200006)35:6<705::AID-JMS997>3.0.CO;2-3 [doi]
PST - ppublish
SO  - J Mass Spectrom. 2000 Jun;35(6):705-10. doi: 
      10.1002/1096-9888(200006)35:6<705::AID-JMS997>3.0.CO;2-3.