PMID- 10865411
OWN - NLM
STAT- MEDLINE
DCOM- 20000721
LR  - 20041117
IS  - 0125-2208 (Print)
IS  - 0125-2208 (Linking)
VI  - 83 Suppl 1
DP  - 2000 Mar
TI  - Fluorescence in situ hybridization: a rapid analysis to verify chromosome 
      aberrations.
PG  - S76-81
AB  - We applied fluorescence in situ hybridization (FISH) to assess the presence of 
      structural rearrangement and numerical chromosome aberrations in both metaphase 
      chromosome and interphase nuclei. For this purpose, the biotinylated repetitive 
      alpha-satellite DNA probes for chromosome 1, 18 and 8 (pUC1.77, L1.84 and pJM128) 
      were used to identify tetraploid mosaicism, ring chromosome 18 and trisomy 8 
      mosaicism for pre-, post-natal and tumor diagnosis respectively. Utilizing this 
      approach, we showed the usefulness of FISH for routine clinical cytogenetics in 
      addition to chromosome banding techniques. The chromosome aberrations with 
      unknown or unclear origin, detected by chromosome analysis, could be confirmed 
      accurately and rapidly.
FAU - Tocharoentanaphol, C
AU  - Tocharoentanaphol C
AD  - Department of Pathology, Faculty of Medicine, Srinakharinwirot University, 
      Bangkok, Thailand.
FAU - Parinayok, R
AU  - Parinayok R
FAU - Punthuwattana, N
AU  - Punthuwattana N
FAU - Kangwanpong, D
AU  - Kangwanpong D
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Thailand
TA  - J Med Assoc Thai
JT  - Journal of the Medical Association of Thailand = Chotmaihet thangphaet
JID - 7507216
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Child, Preschool
MH  - *Chromosome Aberrations
MH  - *Chromosomes, Human, Pair 18
MH  - *Chromosomes, Human, Pair 8
MH  - Female
MH  - Humans
MH  - *In Situ Hybridization, Fluorescence
MH  - Male
MH  - Sensitivity and Specificity
EDAT- 2000/06/24 11:00
MHDA- 2000/08/01 11:00
CRDT- 2000/06/24 11:00
PHST- 2000/06/24 11:00 [pubmed]
PHST- 2000/08/01 11:00 [medline]
PHST- 2000/06/24 11:00 [entrez]
PST - ppublish
SO  - J Med Assoc Thai. 2000 Mar;83 Suppl 1:S76-81.