PMID- 10889335
OWN - NLM
STAT- MEDLINE
DCOM- 20000928
LR  - 20190701
IS  - 0304-3940 (Print)
IS  - 0304-3940 (Linking)
VI  - 288
IP  - 3
DP  - 2000 Jul 21
TI  - Intracortical excitatory and inhibitory phenomena to paired transcranial magnetic 
      stimulation in healthy human subjects: differences between the right and left 
      hemisphere.
PG  - 171-4
AB  - Intracortical inhibition (ICI) and facilitation (ICF) to paired magnetic stimuli 
      reflect the activation of interneuronal circuits within the motor cortex. 
      Intersubjects physiological variability of these phenomena, partly limits the 
      usefulness of such method. Therefore, interhemispheric ICI/ICF differences might 
      represent a more sensitive and less variable neurophysiological parameter to test 
      the motor cortex excitability. Motor evoked potentials from the hand muscles were 
      recorded in ten healthy subjects in a paired-pulse paradigm. Interstimulus 
      intervals (ISIs) from 1 to 50 ms were used. The time course of ICI and ICF in the 
      two hemispheres is consistent with minimal interhemispheric asymmetries. The 
      interhemispheric differences of ICI and ICF could be a valuable 
      neurophysiological marker for the diagnosis, prognosis and follow-up of 
      neurological diseases characterized by monohemispheric damage and lateralized 
      motor deficits.
FAU - Cicinelli, P
AU  - Cicinelli P
AD  - IRCCS Ospedale di Riabilitazione S. Lucia, Rome, Italy.
FAU - Traversa, R
AU  - Traversa R
FAU - Oliveri, M
AU  - Oliveri M
FAU - Palmieri, M G
AU  - Palmieri MG
FAU - Filippi, M M
AU  - Filippi MM
FAU - Pasqualetti, P
AU  - Pasqualetti P
FAU - Rossini, P M
AU  - Rossini PM
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - Ireland
TA  - Neurosci Lett
JT  - Neuroscience letters
JID - 7600130
SB  - IM
MH  - Cerebral Cortex/*physiology
MH  - Electromagnetic Phenomena/*methods
MH  - Evoked Potentials, Motor/physiology
MH  - Excitatory Postsynaptic Potentials/*physiology
MH  - Humans
MH  - Neural Inhibition/*physiology
MH  - Synaptic Transmission/physiology
EDAT- 2000/07/13 11:00
MHDA- 2000/09/30 11:01
CRDT- 2000/07/13 11:00
PHST- 2000/07/13 11:00 [pubmed]
PHST- 2000/09/30 11:01 [medline]
PHST- 2000/07/13 11:00 [entrez]
AID - S0304394000012167 [pii]
AID - 10.1016/s0304-3940(00)01216-7 [doi]
PST - ppublish
SO  - Neurosci Lett. 2000 Jul 21;288(3):171-4. doi: 10.1016/s0304-3940(00)01216-7.