PMID- 10918194
OWN - NLM
STAT- MEDLINE
DCOM- 20000818
LR  - 20160303
IS  - 0020-7136 (Print)
IS  - 0020-7136 (Linking)
VI  - 87
IP  - 4
DP  - 2000 Aug 15
TI  - Decrease of human T-cell lymphotropic virus type I prevalence and low incidence 
      among pregnant women from a high endemic ethnic group in French Guiana.
PG  - 534-8
AB  - To assess the prevalence and incidence of human T-cell lymphotropic virus type I 
      (HTLV-I), 4,234 pregnant women of different ethnic origins were tested before 
      each delivery between 1991 and 1997 in a high HTLV-I endemic area of French 
      Guiana. HTLV-I was significantly more prevalent among ethnic groups of African 
      descent as the Noir-Marrons (4.8%, 95% confidence interval [CI]: 4.0-5.6) and 
      Haitians (5%, 95% CI 1.6-8.4). An age dependence of HTLV-I seroprevalence was 
      observed. The mean age of Noir-Marron HTLV-I seronegative women was lower than 
      for HTLV-I seropositive women (24. 7 vs. 28.6, p < 0.001). A decline in HTLV-I 
      seroprevalence was observed, particularly in the Noir-Marron younger than 21 
      years old (p = 0.04). For five HTLV-I seroconversions observed, the incidence per 
      100 women-years in the Noir-Marron group was 0.19 (95% CI 0.02-0. 35) for all 
      women, 0.32 in those 25 years old or younger (95% CI 0-0. 64), and 0.07 in those 
      older than 25 years (95% CI 0-0.2). This observation was inconsistent with HTLV-I 
      seroprevalence observed for those 25 years old or younger (2.8%) and those older 
      than 25 (8.3%). These data demonstrate, for the first time outside Japan, a birth 
      cohort effect for HTLV-I in a highly endemic ethnic group.
CI  - Copyright 2000 Wiley-Liss, Inc.
FAU - Tortevoye, P
AU  - Tortevoye P
AD  - Unite d'Epidemiologie des Virus Oncogenes, Institut Pasteur, Paris, France.
FAU - Tuppin, P
AU  - Tuppin P
FAU - Peneau, C
AU  - Peneau C
FAU - Carles, G
AU  - Carles G
FAU - Gessain, A
AU  - Gessain A
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Int J Cancer
JT  - International journal of cancer
JID - 0042124
SB  - IM
MH  - Adult
MH  - Africa/ethnology
MH  - Endemic Diseases
MH  - Female
MH  - French Guiana/epidemiology
MH  - HTLV-I Infections/blood/*epidemiology
MH  - *Human T-lymphotropic virus 1
MH  - Humans
MH  - Incidence
MH  - Pregnancy
MH  - Pregnancy Complications, Infectious/blood/*epidemiology
MH  - Prevalence
MH  - Seroepidemiologic Studies
EDAT- 2000/08/05 11:00
MHDA- 2000/08/29 11:01
CRDT- 2000/08/05 11:00
PHST- 2000/08/05 11:00 [pubmed]
PHST- 2000/08/29 11:01 [medline]
PHST- 2000/08/05 11:00 [entrez]
AID - 10.1002/1097-0215(20000815)87:4<534::AID-IJC12>3.0.CO;2-M [pii]
PST - ppublish
SO  - Int J Cancer. 2000 Aug 15;87(4):534-8.