PMID- 10923687
OWN - NLM
STAT- MEDLINE
DCOM- 20010125
LR  - 20190718
IS  - 0959-4965 (Print)
IS  - 0959-4965 (Linking)
VI  - 11
IP  - 10
DP  - 2000 Jul 14
TI  - Modulation of cortical excitability during action observation: a transcranial 
      magnetic stimulation study.
PG  - 2289-92
AB  - Paired-pulse transcranial magnetic stimulation (TMS) was used to examine changes 
      in cortical excitability during action observation. We stimulated the left 
      primary motor cortex (M1) of eight healthy volunteers during rest, observation of 
      handwriting and observation of arm movements. Motor evoked potentials (MEP) were 
      recorded from the first dorsal intereosseous (FDI) and biceps (BIC) muscles. Our 
      results showed that action observation induced a facilitation of the MEP 
      amplitude evoked by the single test stimulus and reduced intracortical inhibition 
      and facilitation at 3 ms and 12 ms interstimulus intervals (ISIs), respectively, 
      during paired-pulse stimulation. These changes were specific for the muscle 
      involved in the observed action. Our study presents further evidence that motor 
      excitability is significantly modified when the subject observes an action 
      performed by another individual.
FAU - Strafella, A P
AU  - Strafella AP
AD  - Montreal Neurological Institute, Quebec, Canada.
FAU - Paus, T
AU  - Paus T
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Neuroreport
JT  - Neuroreport
JID - 9100935
SB  - IM
MH  - Adult
MH  - Brain Mapping
MH  - Cerebral Cortex/*physiology
MH  - Electromyography
MH  - Evoked Potentials, Motor/*physiology
MH  - Feedback
MH  - Female
MH  - Hand/innervation
MH  - Humans
MH  - Male
MH  - Muscle, Skeletal/*innervation
MH  - *Photic Stimulation
MH  - Time Factors
MH  - *Transcranial Magnetic Stimulation
EDAT- 2000/08/03 11:00
MHDA- 2001/02/28 10:01
CRDT- 2000/08/03 11:00
PHST- 2000/08/03 11:00 [pubmed]
PHST- 2001/02/28 10:01 [medline]
PHST- 2000/08/03 11:00 [entrez]
AID - 10.1097/00001756-200007140-00044 [doi]
PST - ppublish
SO  - Neuroreport. 2000 Jul 14;11(10):2289-92. doi: 10.1097/00001756-200007140-00044.