PMID- 10930489
OWN - NLM
STAT- MEDLINE
DCOM- 20000906
LR  - 20190627
IS  - 0002-9610 (Print)
IS  - 0002-9610 (Linking)
VI  - 179
IP  - 5
DP  - 2000 May
TI  - Correlation between physiological assessment and outcome after liver 
      transplantation.
PG  - 396-9
AB  - BACKGROUND: Critical shortages of organ donors for transplantation require 
      appropriate utilization of this scarce resource. The purpose of this study was to 
      assess whether use of physiological parameters of preliver transplant recipients 
      is helpful in determining eventual outcome. METHODS: Between October 1989 and 
      June 1999, 215 liver transplants were performed on 199 patients at the Vancouver 
      Hospital nad Health Sciences Centre. Thirty-one patients undergoing 
      transplantation between May 1993 and June 1994 were retrospectively evaluated to 
      obtain a minimum 5-year follow-up. Variables examined included pretransplant 
      activation status (status 1, at home; status 2, hospitalized; status 3, admitted 
      to intensive care; status 4, mechanical ventilation), simplified acute 
      physiological score (SAPS), Acute Physiology, Age, and Chronic Health Evaluation 
      (APACHE) II, and APACHE III scores at the time of transplantation. The scores 
      were correlated to posttransplant mortality and functional outcome. RESULTS: The 
      5-year mortality for status 1 patients was 14.3% versus 30% for patients listed 
      as status 2 or greater (P = not significant). There were no significant 
      differences in any of the physiological scoring assessments with regard to 
      posttransplant mortality or functional assessment. Of the surviving patients, 18 
      of 22 who were employed, in school, or active at home pretransplant returned to 
      their pretransplant activity. CONCLUSIONS: Detailed physiological scoring systems 
      are no more accurate in predicting outcome after liver transplant than current 
      listing status parameters.
FAU - Chung, S W
AU  - Chung SW
AD  - Departments of Surgery and Medicine, University of British Columbia, and the 
      British Columbia Transplant Society, Vancouver, British Columbia, Canada.
FAU - Kirkpatrick, A W
AU  - Kirkpatrick AW
FAU - Kim, H L
AU  - Kim HL
FAU - Scudamore, C H
AU  - Scudamore CH
FAU - Yoshida, E M
AU  - Yoshida EM
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Am J Surg
JT  - American journal of surgery
JID - 0370473
SB  - IM
MH  - *APACHE
MH  - *Activities of Daily Living
MH  - Analysis of Variance
MH  - Comorbidity
MH  - Contraindications
MH  - Critical Care/statistics & numerical data
MH  - *Health Status
MH  - Hospitalization/*statistics & numerical data
MH  - Humans
MH  - Liver Transplantation/adverse effects/*mortality/*physiology
MH  - Logistic Models
MH  - Predictive Value of Tests
MH  - Prognosis
MH  - Reproducibility of Results
MH  - Retrospective Studies
MH  - Survival Analysis
MH  - Treatment Outcome
EDAT- 2000/08/10 11:00
MHDA- 2000/09/09 11:01
CRDT- 2000/08/10 11:00
PHST- 2000/08/10 11:00 [pubmed]
PHST- 2000/09/09 11:01 [medline]
PHST- 2000/08/10 11:00 [entrez]
AID - S0002-9610(00)00362-7 [pii]
AID - 10.1016/s0002-9610(00)00362-7 [doi]
PST - ppublish
SO  - Am J Surg. 2000 May;179(5):396-9. doi: 10.1016/s0002-9610(00)00362-7.