PMID- 10932493
OWN - NLM
STAT- MEDLINE
DCOM- 20000912
LR  - 20131121
IS  - 0125-2208 (Print)
IS  - 0125-2208 (Linking)
VI  - 83
IP  - 6
DP  - 2000 Jun
TI  - Maintenance ECT in treatment-resistant schizophrenia.
PG  - 657-62
AB  - Although electroconvulsive therapy (ECT) has been used to treat schizophrenia 
      since its inception in 1938, its efficacy as long-term treatment is still 
      controversial. A 2-Phase, prospective study has been conducted in 21 patients 
      with schizophrenia. The duration of study was 1 year. Bilateral ECT combined with 
      flupenthixol (18-24 mg/day) was used throughout. Brief Psychiatric Rating Scale 
      (BPRS), Global Assessment of Functioning (GAF), and Mini-Mental-State Exam (MMSE) 
      were used to measure the outcome. No patients suffered relapses. There were 
      marked reductions in BPRS scores (73 per cent and 70 per cent), and increases in 
      GAF scores (68 per cent and 91 per cent), at the end of Phases I and II, 
      respectively. This study suggests a long-term efficacy of ECT combined with 
      neuroleptic therapy in patients with schizophrenia.
FAU - Chanpattana, W
AU  - Chanpattana W
AD  - Department of Psychiatry, Srinakharinwirot University, Vajira Hospital, Bangkok, 
      Thailand.
LA  - eng
PT  - Clinical Trial
PT  - Clinical Trial, Phase I
PT  - Clinical Trial, Phase II
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Thailand
TA  - J Med Assoc Thai
JT  - Journal of the Medical Association of Thailand = Chotmaihet thangphaet
JID - 7507216
RN  - 0 (Antipsychotic Agents)
RN  - FA0UYH6QUO (Flupenthixol)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Antipsychotic Agents/*administration & dosage
MH  - Brief Psychiatric Rating Scale
MH  - Combined Modality Therapy
MH  - Drug Resistance
MH  - Electroconvulsive Therapy/*methods
MH  - Female
MH  - Flupenthixol/*administration & dosage
MH  - Humans
MH  - Long-Term Care
MH  - Male
MH  - Prognosis
MH  - Prospective Studies
MH  - Schizophrenia/diagnosis/*therapy
MH  - Treatment Failure
MH  - Treatment Outcome
EDAT- 2000/08/10 11:00
MHDA- 2000/09/19 11:01
CRDT- 2000/08/10 11:00
PHST- 2000/08/10 11:00 [pubmed]
PHST- 2000/09/19 11:01 [medline]
PHST- 2000/08/10 11:00 [entrez]
PST - ppublish
SO  - J Med Assoc Thai. 2000 Jun;83(6):657-62.