PMID- 10933463 OWN - NLM STAT- MEDLINE DCOM- 20000829 LR - 20191023 IS - 0392-0461 (Print) IS - 0392-0461 (Linking) VI - 19 IP - 4 DP - 1998 Aug TI - Light chain deposition disease neuropathy resembling amyloid neuropathy in a multiple myeloma patient. PG - 229-33 AB - A 65-year-old man with IgG lambda multiple myeloma developed severe polyneuropathy with prominent thermal-pain sensory impairment and autonomic failure. Although the clinical presentation suggested amyloid neuropathy, nerve biopsy showed the immunohistochemical and ultrastructural features typical of light chain deposition disease (LCDD). A precise morphologic and clinical description of LCDD neuropathy is given for the first time in the present report. FAU - Grassi, M P AU - Grassi MP AD - Department of Neurology, L. Sacco Hospital, Milan, Italy. FAU - Clerici, F AU - Clerici F FAU - Perin, C AU - Perin C FAU - Borella, M AU - Borella M FAU - Gendarini, A AU - Gendarini A FAU - Quattrini, A AU - Quattrini A FAU - Nemni, R AU - Nemni R FAU - Mangoni, A AU - Mangoni A LA - eng PT - Case Reports PT - Journal Article PL - Italy TA - Ital J Neurol Sci JT - Italian journal of neurological sciences JID - 8006502 RN - 0 (Immunoglobulin Light Chains) SB - IM MH - Aged MH - Amyloidosis/immunology/*pathology MH - Biopsy MH - Fluorescent Antibody Technique MH - Humans MH - Immunoglobulin Light Chains/*analysis MH - Male MH - Microscopy, Electron MH - Multiple Myeloma/immunology/*pathology MH - Polyneuropathies/immunology/*pathology MH - Sural Nerve/chemistry/pathology/ultrastructure EDAT- 2000/08/10 11:00 MHDA- 2000/09/02 11:01 CRDT- 2000/08/10 11:00 PHST- 2000/08/10 11:00 [pubmed] PHST- 2000/09/02 11:01 [medline] PHST- 2000/08/10 11:00 [entrez] AID - 10.1007/BF02427609 [doi] PST - ppublish SO - Ital J Neurol Sci. 1998 Aug;19(4):229-33. doi: 10.1007/BF02427609.