PMID- 10935773
OWN - NLM
STAT- MEDLINE
DCOM- 20010108
LR  - 20191104
IS  - 1401-7431 (Print)
IS  - 1401-7431 (Linking)
VI  - 34
IP  - 3
DP  - 2000 Jun
TI  - Cardiac rhythm in patients with sleep-disordered breathing and coronary artery 
      disease.
PG  - 272-6
AB  - We examined the effect of sleep-disordered breathing on heart rates and 
      arrhythmias in men and women with disabling angina pectoris and verified coronary 
      artery disease by an overnight sleep study and Holter recording. The number of 
      oxyhaemoglobin desaturations > or =4% (ODI) and number of apnoea-hypopnoeas per 
      hour of sleep (AHI) were recorded. ODI > or =5 and AHI > or =10 were used as 
      measures of disordered breathing and patients below these limits formed the 
      control groups. One-hundred and forty-one men and 98 women < or =70 years of age 
      were randomly included. Thirty-eight percent of the men and 36% of the women had 
      an ODI > or =5. No serious ventricular arrhythmias occurred. Women with 
      disordered breathing (ODI > or =5) had higher heart rates (mean 63.3 vs 59.1, p < 
      0.05) and a higher occurrence of ventricular premature contractions (VPCs) during 
      sleep (75th percentiles 2.5 vs 0.5 per hour, p < 0.01). In men, however, no 
      significant association between disordered breathing and heart rates or 
      arrhythmias was found. We conclude that serious arrhythmias are infrequent in 
      unselected patients with coronary artery disease and mild to moderate 
      sleep-disordered breathing. Disordered breathing in women is associated with 
      higher heart rates and a higher occurrence of VPCs during sleep.
FAU - Mooe, T
AU  - Mooe T
AD  - Department of Cardiology, University Hospital, Umea, Sweden. 
      thomas.mooe@medicin.umu.se
FAU - Franklin, K A
AU  - Franklin KA
FAU - Wiklund, U
AU  - Wiklund U
FAU - Rabben, T
AU  - Rabben T
FAU - Holmstrom, K
AU  - Holmstrom K
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Scand Cardiovasc J
JT  - Scandinavian cardiovascular journal : SCJ
JID - 9708377
SB  - IM
MH  - Aged
MH  - Angina Pectoris/diagnosis
MH  - Arrhythmias, Cardiac/*diagnosis
MH  - Coronary Disease/*diagnosis
MH  - *Electrocardiography
MH  - Electrocardiography, Ambulatory
MH  - Female
MH  - Heart Rate
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Polysomnography
MH  - Sex Factors
MH  - Sleep Apnea, Obstructive/*diagnosis
MH  - Ventricular Dysfunction, Left/diagnosis
MH  - Ventricular Premature Complexes/diagnosis
EDAT- 2000/08/10 11:00
MHDA- 2001/02/28 10:01
CRDT- 2000/08/10 11:00
PHST- 2000/08/10 11:00 [pubmed]
PHST- 2001/02/28 10:01 [medline]
PHST- 2000/08/10 11:00 [entrez]
AID - 10.1080/713783116 [doi]
PST - ppublish
SO  - Scand Cardiovasc J. 2000 Jun;34(3):272-6. doi: 10.1080/713783116.