PMID- 10949007
OWN - NLM
STAT- MEDLINE
DCOM- 20001214
LR  - 20190831
IS  - 0195-9131 (Print)
IS  - 0195-9131 (Linking)
VI  - 32
IP  - 8
DP  - 2000 Aug
TI  - Macronutrient intake and whole body protein metabolism following resistance 
      exercise.
PG  - 1412-8
AB  - The provision of carbohydrate (CHO) supplements following resistance exercise 
      attenuated muscle protein (PRO) degradation (Roy et al. J. Appl. Physiol. 
      82:1882-1888, 1997). The addition of PRO may have a synergistic effect upon whole 
      body protein balance by increasing synthesis (Biolo et al. Am. J. Physiol. 
      273:E122-E129, 1997). PURPOSE: To determine if the macronutrient composition of a 
      postexercise beverage would alter muscle anabolism and/or catabolism following 
      resistance exercise. METHODS: We provided isoenergetic CHO (1 g x kg(-1)) and 
      CHO/PRO/FAT supplements and placebo (PL) immediately (t = 0 h) and 1 h (t = + 1 
      h) following resistance exercise (9 exercises/3 sets/80% 1 RM) to 10 young, 
      healthy, resistance-trained males. Whole body leucine turnover was determined 
      from L-[1-13C]leucine kinetics at approximately 4 h postexercise. RESULTS: No 
      differences were observed for urinary 3-methylhistidine or urea nitrogen 
      excretion between the trials. Leucine flux was significantly elevated at 
      approximately 4 h postexercise for both CHO/PRO/FAT (177.59+/-12.68 micromol x 
      kg(-1) x h(-1)) and CHO (156.18+/-7.77 micromol x kg(-1) x h(-1)) versus PL 
      (126.32+/-10.51 micromol x kg(-1) x h(-1)) (P < 0.01). Whole body leucine 
      oxidation was elevated at approximately 4 h for CHO/PRO/FAT (29.50+/-3.34 
      micromol x kg(-1) h(-1)) versus CHO (16.32+/-2.33 micromol x kg(-1) x h(-1)) (P < 
      0.01) and PL (21.29+/-2.54 micromol x kg(-1) x h(-1)) (P < 0.05). Nonoxidative 
      leucine disposal (NOLD) was significantly elevated at approximately 4 h for both 
      CHO/PRO/FAT (148.09+/-10.37 micromol x kg(-1) x h(-1)) and CHO (139.86+/-7.02 
      micromol x kg(-1) x h(-1)) versus PL (105.03+/-8.97 micromol x kg(-1) x h(-1)) (P 
      < 0.01). CONCLUSIONS: These results suggest that consumption of either CHO or 
      CHO/PRO/FAT immediately and 1 h following a resistance training bout increased 
      NOLD as compared with a placebo.
FAU - Roy, B D
AU  - Roy BD
AD  - Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada.
FAU - Fowles, J R
AU  - Fowles JR
FAU - Hill, R
AU  - Hill R
FAU - Tarnopolsky, M A
AU  - Tarnopolsky MA
LA  - eng
PT  - Clinical Trial
PT  - Controlled Clinical Trial
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Med Sci Sports Exerc
JT  - Medicine and science in sports and exercise
JID - 8005433
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Fats)
RN  - 0 (Dietary Proteins)
RN  - 0 (Placebos)
RN  - 0 (Proteins)
SB  - IM
MH  - Adult
MH  - Breath Tests
MH  - Dietary Carbohydrates/*administration & dosage
MH  - Dietary Fats/*administration & dosage
MH  - Dietary Proteins/*administration & dosage
MH  - Double-Blind Method
MH  - Exercise
MH  - Humans
MH  - Male
MH  - Placebos
MH  - Proteins/*metabolism
MH  - Weight Lifting/*physiology
EDAT- 2000/08/19 11:00
MHDA- 2001/02/28 10:01
CRDT- 2000/08/19 11:00
PHST- 2000/08/19 11:00 [pubmed]
PHST- 2001/02/28 10:01 [medline]
PHST- 2000/08/19 11:00 [entrez]
AID - 10.1097/00005768-200008000-00009 [doi]
PST - ppublish
SO  - Med Sci Sports Exerc. 2000 Aug;32(8):1412-8. doi: 
      10.1097/00005768-200008000-00009.