PMID- 10958173
OWN - NLM
STAT- MEDLINE
DCOM- 20001222
LR  - 20190921
IS  - 0891-6934 (Print)
IS  - 0891-6934 (Linking)
VI  - 32
IP  - 1
DP  - 2000
TI  - Serum anti-S100b, anti-GFAP and anti-NGF autoantibodies of IgG class in healthy 
      persons and patients with mental and neurological disorders.
PG  - 33-8
AB  - Natural autoantibodies of IgG class to proteins S100b, glial fibrillar acidic 
      protein (GFAP), and nerve growth factor (NGF) are presented in serum of healthy 
      adults and those levels/affinities are relatively constant and may vary among 
      individuals within narrow limits. In patients with depressive disorder, epilepsy, 
      multiple sclerosis, and Parkinson's disease dispersion of such autoantibodies 
      serum levels were often found beyond the normal ranges. Most of the patient 
      groups include cases with significantly elevated as well as abnormally decreased 
      immunoreactivity parameters. This leads us to assumption that changes in some 
      basic mechanisms of individual immune state represent the common features of 
      different forms of pathology of the nervous system.
FAU - Poletaev, A B
AU  - Poletaev AB
AD  - Biomedical Chemistry, Russian Academy of Medical Sciences, Moscow. 
      vtchernn@cityline.ru
FAU - Morozov, S G
AU  - Morozov SG
FAU - Gnedenko, B B
AU  - Gnedenko BB
FAU - Zlunikin, V M
AU  - Zlunikin VM
FAU - Korzhenevskey, D A
AU  - Korzhenevskey DA
LA  - eng
PT  - Journal Article
PL  - England
TA  - Autoimmunity
JT  - Autoimmunity
JID - 8900070
RN  - 0 (Autoantibodies)
RN  - 0 (Calcium-Binding Proteins)
RN  - 0 (Glial Fibrillary Acidic Protein)
RN  - 0 (Immunoglobulin G)
RN  - 0 (Nerve Growth Factors)
RN  - 0 (Nerve Tissue Proteins)
RN  - 0 (S100 Calcium Binding Protein beta Subunit)
RN  - 0 (S100 Proteins)
RN  - 0 (S100B protein, human)
RN  - 9061-61-4 (Nerve Growth Factor)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Antibody Affinity
MH  - Autoantibodies/*blood
MH  - Calcium-Binding Proteins/*immunology
MH  - Female
MH  - Glial Fibrillary Acidic Protein/*immunology
MH  - Humans
MH  - Immunoblotting
MH  - Immunoglobulin G/*analysis
MH  - Male
MH  - Mental Disorders/*immunology
MH  - Middle Aged
MH  - Nerve Growth Factor/*immunology
MH  - Nerve Growth Factors/*immunology
MH  - Nerve Tissue Proteins/immunology
MH  - Nervous System Diseases/*immunology
MH  - S100 Calcium Binding Protein beta Subunit
MH  - *S100 Proteins
EDAT- 2000/08/25 11:00
MHDA- 2001/02/28 10:01
CRDT- 2000/08/25 11:00
PHST- 2000/08/25 11:00 [pubmed]
PHST- 2001/02/28 10:01 [medline]
PHST- 2000/08/25 11:00 [entrez]
AID - I350C001003 [pii]
AID - 10.3109/08916930008995985 [doi]
PST - ppublish
SO  - Autoimmunity. 2000;32(1):33-8. doi: 10.3109/08916930008995985.