PMID- 10959497
OWN - NLM
STAT- MEDLINE
DCOM- 20001207
LR  - 20190915
IS  - 0148-5016 (Print)
IS  - 0148-5016 (Linking)
VI  - 45
IP  - 1
DP  - 2000 Jul-Aug
TI  - Detection of chromosome 15 deletion in Prader-Willi syndrome using fluorescence 
      in situ hybridization.
PG  - 13-7
AB  - Deletion of chromosome 15 was investigated in 6 patients with Prader-Willi 
      syndrome (PWS) using chromosome and fluorescence in situ hybridization (FISH) 
      analysis. Although chromosome analysis using G-banding methods revealed the 
      deletion of 15q11-q13 in only 3 cases, staining by FISH using D15S11 and/or small 
      nuclear ribonucleoprotein polypeptide N (SNRPN) probes detected chromosome 15 
      deletion in all cases. It would appear that FISH analysis is an effective 
      diagnostic test for the detection of chromosome 15 deletion in patients with PWS.
FAU - Suzuki, Y
AU  - Suzuki Y
AD  - Department of Urology, Yamagata University School of Medicine, Japan.
FAU - Sasagawa, I
AU  - Sasagawa I
FAU - Yazawa, H
AU  - Yazawa H
FAU - Tateno, T
AU  - Tateno T
FAU - Nakada, T
AU  - Nakada T
LA  - eng
PT  - Journal Article
PL  - England
TA  - Arch Androl
JT  - Archives of andrology
JID - 7806755
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Child
MH  - Child, Preschool
MH  - Chromosome Banding
MH  - *Chromosome Deletion
MH  - *Chromosomes, Human, Pair 15
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Karyotyping
MH  - Prader-Willi Syndrome/*genetics
EDAT- 2000/08/26 11:00
MHDA- 2001/02/28 10:01
CRDT- 2000/08/26 11:00
PHST- 2000/08/26 11:00 [pubmed]
PHST- 2001/02/28 10:01 [medline]
PHST- 2000/08/26 11:00 [entrez]
AID - 10.1080/014850100409963 [doi]
PST - ppublish
SO  - Arch Androl. 2000 Jul-Aug;45(1):13-7. doi: 10.1080/014850100409963.