PMID- 10962960
OWN - NLM
STAT- MEDLINE
DCOM- 20000920
LR  - 20061115
IS  - 0041-5782 (Print)
IS  - 0041-5782 (Linking)
VI  - 162
IP  - 33
DP  - 2000 Aug 14
TI  - [Dendritic cells--and their possible applications in cancer therapy].
PG  - 4377-81
AB  - Dendritic cells (DCs) represent a group of antigen-presenting leukocytes which 
      are very effective in activating resting T-cells. DCs are present in almost all 
      tissues of the body, but they are generally difficult to isolate. The study of 
      human DCs has recently become greatly facilitated due to the advent of methods 
      for isolation and in vivo generation of DCs from blood. Experiments in animal 
      models have shown that DCs loaded with tumour antigens may induce effective 
      immune responses against cancer. Now the potential of vaccination with tumour 
      antigens presented on DCs is being evaluated in cancer patients. Preliminary 
      clinical studies have shown encouraging results.
FAU - Agger, R
AU  - Agger R
AD  - Institut for Medicinsk Mikrobiologi & Immunologi, Aarhus Universitet.
FAU - Hokland, M E
AU  - Hokland ME
LA  - dan
PT  - English Abstract
PT  - Journal Article
PT  - Review
TT  - Dendritiske celler--og deres anvendelsesmuligheder i cancerterapi.
PL  - Denmark
TA  - Ugeskr Laeger
JT  - Ugeskrift for laeger
JID - 0141730
RN  - 0 (Antigens, Neoplasm)
SB  - IM
CIN - Ugeskr Laeger. 2000 Oct 30;162(44):5940-1. PMID: 11094562
MH  - Animals
MH  - Antigen-Presenting Cells/immunology/ultrastructure
MH  - Antigens, Neoplasm/immunology
MH  - Cell Separation
MH  - *Dendritic Cells/immunology/ultrastructure
MH  - Humans
MH  - Immunotherapy
MH  - Lymphocyte Activation
MH  - Neoplasms/*therapy
MH  - T-Lymphocytes/immunology
RF  - 16
EDAT- 2000/08/30 11:00
MHDA- 2000/09/23 11:01
CRDT- 2000/08/30 11:00
PHST- 2000/08/30 11:00 [pubmed]
PHST- 2000/09/23 11:01 [medline]
PHST- 2000/08/30 11:00 [entrez]
PST - ppublish
SO  - Ugeskr Laeger. 2000 Aug 14;162(33):4377-81.