PMID- 10965124 OWN - NLM STAT- MEDLINE DCOM- 20000921 LR - 20200310 IS - 0301-0171 (Print) IS - 0301-0171 (Linking) VI - 89 IP - 3-4 DP - 2000 TI - Comparative mapping of seven genes in mouse, rat and Chinese hamster chromosomes by fluorescence in situ hybridization. PG - 209-13 AB - By fluorescence in situ hybridization (FISH) using mouse probes, we assigned homologues for cathepsin E (Ctse), protocadherin 10 (Pcdh10, alias OL-protocadherin, Ol-pc), protocadherin 13 (Pcdh13, alias protocadherin 2c, Pcdh2c), neuroglycan C (Cspg5) and myosin X (Myo10) genes to rat chromosomes (RNO) 13q13, 2q24-->q25, 18p12-->p11, 8q32.1 and 2q22.1-->q22.3, respectively. Similarly, homologues for mouse Ctse, Pcdh13, Cspg5 and Myo10 genes and homologues for rat Smad2 (Madh2) and Smad4 (Madh4) genes were assigned to Chinese hamster chromosomes (CGR) 5q28, 2q17, 4q26, 2p29-->p27, 2q112-->q113 and 2q112-->q113, respectively. The chromosome assignments of homologues of Ctse and Cspg5 reinforced well-known homologous relationships among mouse chromosome (MMU) 1, RNO 13 and CGR 5q, and among MMU 9, RNO 8 and CGR 4q, respectively. The chromosome locations of homologues for Madh2, Madh4 and Pcdh13 genes suggested that inversion events were involved in chromosomal rearrangements in the differentiation of MMU 18 and RNO 18, whereas most of MMU 18 is conserved as a continuous segment in CGR 2q. Furthermore, the mapping result of Myo10 and homologues suggested an orthologous segment of MMU 15, RNO 2 and CGR 2. CI - Copyright 2000 S. Karger AG, Basel. FAU - Ono, T AU - Ono T AD - Department of Genetics, Institute for Developmental Research, Aichi Human Service Center, Kasugai, Japan. FAU - Hirano, S AU - Hirano S FAU - Yonezawa, S AU - Yonezawa S FAU - Aono, S AU - Aono S FAU - Osaki, M AU - Osaki M FAU - Masaki, S AU - Masaki S FAU - Yamashita, S AU - Yamashita S FAU - Tsukasaki, T AU - Tsukasaki T FAU - Oohira, A AU - Oohira A FAU - Suzuki, S T AU - Suzuki ST FAU - Sonta, S AU - Sonta S LA - eng PT - Comparative Study PT - Journal Article PL - Switzerland TA - Cytogenet Cell Genet JT - Cytogenetics and cell genetics JID - 0367735 RN - 0 (Cadherins) RN - 0 (Cspg5 protein, mouse) RN - 0 (Cspg5 protein, rat) RN - 0 (DNA-Binding Proteins) RN - 0 (Membrane Proteins) RN - 0 (Myo10 protein, mouse) RN - 0 (Proteoglycans) RN - 0 (Smad2 Protein) RN - 0 (Smad2 protein, mouse) RN - 0 (Smad2 protein, rat) RN - 0 (Smad4 Protein) RN - 0 (Smad4 protein, mouse) RN - 0 (Smad4 protein, rat) RN - 0 (Trans-Activators) RN - EC 3.4.23.34 (Cathepsin E) RN - EC 3.6.4.1 (Myosins) SB - IM MH - Animals MH - Cadherins/genetics MH - Cathepsin E/genetics MH - Chromosome Mapping MH - Cricetinae MH - DNA-Binding Proteins/genetics MH - Genes/*genetics MH - In Situ Hybridization, Fluorescence MH - Membrane Proteins/genetics MH - Mice MH - Myosins/genetics MH - Proteoglycans/genetics MH - Rats MH - Smad2 Protein MH - Smad4 Protein MH - Trans-Activators/genetics EDAT- 2000/08/31 11:00 MHDA- 2000/09/23 11:01 CRDT- 2000/08/31 11:00 PHST- 2000/08/31 11:00 [pubmed] PHST- 2000/09/23 11:01 [medline] PHST- 2000/08/31 11:00 [entrez] AID - 15614 [pii] AID - 10.1159/000015614 [doi] PST - ppublish SO - Cytogenet Cell Genet. 2000;89(3-4):209-13. doi: 10.1159/000015614.