PMID- 10966235
OWN - NLM
STAT- MEDLINE
DCOM- 20000908
LR  - 20200305
IS  - 0022-2615 (Print)
IS  - 0022-2615 (Linking)
VI  - 49
IP  - 9
DP  - 2000 Sep
TI  - Clonal spread of an invasive strain of Haemophilus influenzae type b among 
      nursery contacts accompanied by a high carriage rate of non-disease-associated 
      strains.
PG  - 845-847
LID - 10.1099/0022-1317-49-9-845 [doi]
AB  - Haemophilus influenza carriage was examined in unvaccinated nursery contacts of a 
      patient with H. influenzae type b (Hib) meningitis and isolates were typed by 
      pulsed-field gel electrophoresis (PFGE). Nasopharyngeal isolates were classified 
      into eight PFGE patterns. Seven Hib carriers were found among 15 nursery 
      contacts. The isolates from the carriers showed a PFGE pattern identical to that 
      of the meningitis strain. The carrier rate of non-disease-associated strains was 
      also high (47%, 7 of 15). This study suggests that the clonal spread of invasive 
      (serotype b) H. influenzae strains is accompanied by a high carriage rate of 
      non-disease-associated strains.
FAU - Saito, Mitsumasa
AU  - Saito M
AD  - Departments of *Bacteriology and daggerPaedriatrics, Graduate School of Medical 
      Sciences, Kyushu University and double daggerDepartment of Clinical Laboratory, Kyushu 
      University Hospital, Fukuoka 812-8582, Japan.
FAU - Okada, Kenji
AU  - Okada K
AD  - Departments of *Bacteriology and daggerPaedriatrics, Graduate School of Medical 
      Sciences, Kyushu University and double daggerDepartment of Clinical Laboratory, Kyushu 
      University Hospital, Fukuoka 812-8582, Japan.
FAU - Takemori, Kouichi
AU  - Takemori K
AD  - Departments of *Bacteriology and daggerPaedriatrics, Graduate School of Medical 
      Sciences, Kyushu University and double daggerDepartment of Clinical Laboratory, Kyushu 
      University Hospital, Fukuoka 812-8582, Japan.
FAU - Yoshida, Shin-Ichi
AU  - Yoshida SI
AD  - Departments of *Bacteriology and daggerPaedriatrics, Graduate School of Medical 
      Sciences, Kyushu University and double daggerDepartment of Clinical Laboratory, Kyushu 
      University Hospital, Fukuoka 812-8582, Japan.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - England
TA  - J Med Microbiol
JT  - Journal of medical microbiology
JID - 0224131
SB  - IM
MH  - *Carrier State
MH  - *Contact Tracing
MH  - Electrophoresis, Gel, Pulsed-Field
MH  - Female
MH  - Haemophilus influenzae/classification/*pathogenicity
MH  - Humans
MH  - Infant
MH  - Japan/epidemiology
MH  - Male
MH  - Meningitis, Haemophilus/*epidemiology
MH  - Nasopharynx/microbiology
MH  - *Nurseries, Infant
EDAT- 2000/08/31 11:00
MHDA- 2000/09/19 11:01
CRDT- 2000/08/31 11:00
PHST- 2000/08/31 11:00 [pubmed]
PHST- 2000/09/19 11:01 [medline]
PHST- 2000/08/31 11:00 [entrez]
AID - 10.1099/0022-1317-49-9-845 [doi]
PST - ppublish
SO  - J Med Microbiol. 2000 Sep;49(9):845-847. doi: 10.1099/0022-1317-49-9-845.