PMID- 10967196
OWN - NLM
STAT- MEDLINE
DCOM- 20010607
LR  - 20220408
IS  - 0109-5641 (Print)
IS  - 0109-5641 (Linking)
VI  - 16
IP  - 6
DP  - 2000 Nov
TI  - Antibacterial effect of silver-zeolite on oral bacteria under anaerobic 
      conditions.
PG  - 452-5
AB  - OBJECTIVES: The purpose of this study was to evaluate the antibacterial effect of 
      silver-zeolite (SZ) against oral bacteria under anaerobic conditions. METHODS: 
      The antibacterial activity of SZ was evaluated by determining the minimum 
      inhibitory concentrations (MICs) using two-fold serial dilutions of SZ in Brain 
      Heart Infusion broth. Release of Ag+ into the broth was measured by an atomic 
      absorption technique. RESULTS: SZ inhibited the growth of the bacteria tested 
      under anaerobic conditions. The MIC of SZ ranged between 256 and 2048 
      micrograms/ml, which corresponded to a range of 4.8-38.4 micrograms/ml of Ag+. 
      All strains grew in broth containing 16,384 micrograms/ml of type-A zeolite. 
      SIGNIFICANCE: These results suggested that SZ may be a useful vehicle to provide 
      antibacterial activity to dental materials used even under anaerobic conditions 
      such as deep in the periodontal pocket.
FAU - Kawahara, K
AU  - Kawahara K
AD  - Department of Preventive Dentistry, Faculty of Dentistry, Hiroshima University, 
      1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan. kawahara@hiroshima-u.ac.jp
FAU - Tsuruda, K
AU  - Tsuruda K
FAU - Morishita, M
AU  - Morishita M
FAU - Uchida, M
AU  - Uchida M
LA  - eng
PT  - Journal Article
PL  - England
TA  - Dent Mater
JT  - Dental materials : official publication of the Academy of Dental Materials
JID - 8508040
RN  - 0 (Anti-Infective Agents, Local)
RN  - 0 (Silver Compounds)
RN  - 1318-02-1 (Zeolites)
MH  - Anaerobiosis
MH  - Anti-Infective Agents, Local/*pharmacology
MH  - Bacteria, Anaerobic/*drug effects
MH  - Microbial Sensitivity Tests
MH  - Mouth/microbiology
MH  - Silver Compounds/chemistry/*pharmacology
MH  - Spectrophotometry, Atomic
MH  - Zeolites/*pharmacology
EDAT- 2000/09/01 11:00
MHDA- 2001/06/08 10:01
CRDT- 2000/09/01 11:00
PHST- 2000/09/01 11:00 [pubmed]
PHST- 2001/06/08 10:01 [medline]
PHST- 2000/09/01 11:00 [entrez]
AID - S0109564100000506 [pii]
AID - 10.1016/s0109-5641(00)00050-6 [doi]
PST - ppublish
SO  - Dent Mater. 2000 Nov;16(6):452-5. doi: 10.1016/s0109-5641(00)00050-6.