PMID- 10970947
OWN - NLM
STAT- MEDLINE
DCOM- 20001113
LR  - 20161031
IS  - 0003-4266 (Print)
IS  - 0003-4266 (Linking)
VI  - 61
IP  - 3
DP  - 2000 Sep
TI  - [Pituitary pathology and MEN 1].
PG  - 214-23
AB  - Multiple Endocrine Neoplasia type 1 (MEN 1) is an autosomal dominant syndrome 
      characterized by neoplasia of the parathyroid glands, the endocrine pancreas and 
      the anterior pituitary gland. Recently the identification on chromosome 11 (locus 
      q13) of the gene responsible for MEN 1 has allowed direct genetic diagnosis of 
      MEN 1-affected family members. To date almost 300 families have been described 
      and genetically characterized. The genetic etiology of most pituitary tumours 
      remains unknown. Pituitary adenomas can develop sporadically or as a part of 
      multiple endocrine neoplasia type 1. In this review, the recently published data 
      on the pathology of the MEN 1 syndrome will be summarized. The clinical, 
      morphological and genetic aspects of sporadic and MEN 1-associated pituitary 
      adenomas will be outlined.
FAU - Betea, D
AU  - Betea D
AD  - Service d'Endocrinologie, CHU de Liege, 4000 Liege, Belgique.
FAU - Valdes Socin, H
AU  - Valdes Socin H
FAU - Beckers, A
AU  - Beckers A
LA  - fre
PT  - English Abstract
PT  - Historical Article
PT  - Journal Article
PT  - Review
TT  - Pathologie hypophysaire et NEM 1.
PL  - France
TA  - Ann Endocrinol (Paris)
JT  - Annales d'endocrinologie
JID - 0116744
SB  - IM
MH  - Adenoma/genetics/history/pathology
MH  - Chromosomes, Human, Pair 11
MH  - Female
MH  - History, 20th Century
MH  - Humans
MH  - Male
MH  - Multiple Endocrine Neoplasia Type 1/*genetics/history/pathology
MH  - Mutation
MH  - Pituitary Neoplasms/*genetics/history/pathology
RF  - 83
EDAT- 2000/09/06 11:00
MHDA- 2001/02/28 10:01
CRDT- 2000/09/06 11:00
PHST- 2000/09/06 11:00 [pubmed]
PHST- 2001/02/28 10:01 [medline]
PHST- 2000/09/06 11:00 [entrez]
AID - MDOI-AE-09-2000-61-3-00034266-101019-ART1 [pii]
PST - ppublish
SO  - Ann Endocrinol (Paris). 2000 Sep;61(3):214-23.