PMID- 10979195
OWN - NLM
STAT- MEDLINE
DCOM- 20001010
LR  - 20191104
IS  - 0905-6947 (Print)
IS  - 0905-6947 (Linking)
VI  - 10
IP  - 3
DP  - 2000 Sep
TI  - An outbreak of respiratory diseases among workers at a water-damaged building--a 
      case report.
PG  - 138-45
AB  - We describe a military hospital building with severe, repeated and enduring water 
      and mold damage, and the symptoms and diseases found among 14 persons who were 
      employed at the building. The exposure of the employees was evaluated by 
      measuring the serum immunoglobulin G (IgG)-antibodies against eight spieces of 
      mold and yeast common in Finnish water and mold damaged buildings and by sampling 
      airborne viable microbes within the hospital. The most abundant spieces was 
      Sporobolomyces salmonicolor. All but one of the employees reported some 
      building-related symptoms, the most common being a cough which was reported by 
      nine subjects. Four new cases of asthma, confirmed by S. salmonicolor inhalation 
      provocation tests, one of whom was also found to have alveolitis, were found 
      among the hospital personnel. In addition, seven other workers with newly 
      diagnosed rhinitis reacted positively in nasal S. salmonicolor provocation tests. 
      Skin prick tests by Sporobolomyces were negative among all 14 workers. Exposure 
      of the workers to mold and yeast in the indoor air caused an outbreak of 
      occupational diseases, including asthma, rhinitis and alveolitis. The diseases 
      were not immunoglobulin E (IgE)-mediated but might have been borne by some other, 
      as yet unexplained, mechanism.
FAU - Seuri, M
AU  - Seuri M
AD  - Kuopio Regional Institute of Occupational Health, Finland. 
      markku.seuri@occuphealth.fi
FAU - Husman, K
AU  - Husman K
FAU - Kinnunen, H
AU  - Kinnunen H
FAU - Reiman, M
AU  - Reiman M
FAU - Kreus, R
AU  - Kreus R
FAU - Kuronen, P
AU  - Kuronen P
FAU - Lehtomaki, K
AU  - Lehtomaki K
FAU - Paananen, M
AU  - Paananen M
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Indoor Air
JT  - Indoor air
JID - 9423515
RN  - 059QF0KO0R (Water)
SB  - IM
MH  - Adult
MH  - Air Pollution, Indoor/*adverse effects
MH  - Asthma/etiology
MH  - Female
MH  - Fungi
MH  - Hospitals, Military
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Occupational Exposure
MH  - Respiratory Tract Diseases/*etiology
MH  - Rhinitis/etiology
MH  - Sick Building Syndrome/etiology
MH  - Water
MH  - Yeasts
EDAT- 2000/09/09 11:00
MHDA- 2000/10/14 11:01
CRDT- 2000/09/09 11:00
PHST- 2000/09/09 11:00 [pubmed]
PHST- 2000/10/14 11:01 [medline]
PHST- 2000/09/09 11:00 [entrez]
AID - 10.1034/j.1600-0668.2000.010003138.x [doi]
PST - ppublish
SO  - Indoor Air. 2000 Sep;10(3):138-45. doi: 10.1034/j.1600-0668.2000.010003138.x.