PMID- 10983573 OWN - NLM STAT- MEDLINE DCOM- 20001004 LR - 20041118 IS - 0265-203X (Print) IS - 0265-203X (Linking) VI - 17 IP - 7 DP - 2000 Jul TI - Pesticide residues variability and acute dietary risk assessment: a consumer perspective. PG - 511-7 AB - In relation to residue variability and acute dietary intake, this paper considers whether or not consumers are adequately protected, and makes recommendations for governments and international bodies. Existing risk assessment science is inadequate to lay to rest some concerns raised by the scientific community, and it is plausible that acute exposures to pesticides from the most contaminated food may be causing adverse effects in some consumers. Consumers International recommends that: (1) analysis and regulation of pesticides with a common mechanism of action (e.g. organophosphate insecticides) be conducted in an integrated, aggregated manner, not on a single pesticide basis; (2) exposure to pesticides in foods consumed in large amounts by children be reduced by revising good agricultural practices; (3) clear risk assessment policies for acute risk assessments be established at the national and international level; and (4) an additional safety factor be applied in order to protect children when establishing maximum residue limits (MRLs) for pesticides in the absence of reliable data on the effects of pesticides on children (e.g. no pesticide-specific tests on immature animals for effects on the developing brain, endocrine, or immune systems). FAU - Lefferts, L Y AU - Lefferts LY AD - llefferts@earthlink.net LA - eng PT - Journal Article PL - England TA - Food Addit Contam JT - Food additives and contaminants JID - 8500474 RN - 0 (Insecticides) RN - 0 (Organophosphorus Compounds) RN - 0 (Pesticide Residues) SB - IM MH - Adult MH - Agriculture/methods MH - Child MH - Child, Preschool MH - *Consumer Product Safety MH - Female MH - Food Contamination/legislation & jurisprudence/*prevention & control MH - Humans MH - Insecticides/*poisoning MH - Male MH - Maximum Allowable Concentration MH - *Organophosphorus Compounds MH - Pesticide Residues/*poisoning MH - Risk Assessment/*methods EDAT- 2000/09/13 11:00 MHDA- 2000/10/07 11:01 CRDT- 2000/09/13 11:00 PHST- 2000/09/13 11:00 [pubmed] PHST- 2000/10/07 11:01 [medline] PHST- 2000/09/13 11:00 [entrez] AID - 10.1080/026520300412401 [doi] PST - ppublish SO - Food Addit Contam. 2000 Jul;17(7):511-7. doi: 10.1080/026520300412401.