PMID- 10997163
OWN - NLM
STAT- MEDLINE
DCOM- 20001120
LR  - 20190910
IS  - 0003-1488 (Print)
IS  - 0003-1488 (Linking)
VI  - 217
IP  - 6
DP  - 2000 Sep 15
TI  - Comparison of serologic testing and slaughter evaluation for assessing the 
      effects of subclinical infection on growth in pigs.
PG  - 888-95
AB  - OBJECTIVE: To compare serologic testing with slaughter evaluation in assessing 
      effects of subclinical infection on average daily weight gain (ADG) in pigs. 
      DESIGN: Cohort study. ANIMALS: 18 cohorts (30 to 35 pigs/cohort) of pigs 
      on/farms. PROCEDURE: Blood samples were collected, and pigs were weighed at 8, 
      16, and 24 weeks of age. Sera were tested for antibodies to porcine reproductive 
      and respiratory syndrome virus (PRRSV), swine influenza virus (SIV), 
      transmissible gastroenteritis virus (TGEV), pseudorabies virus, Mycoplasma 
      hyopneumoniae, and Actinobacillus pleuropneumoniae. At slaughter, skin, nasal 
      turbinates, lungs, and liver were examined. Associations between ADG and results 
      of serologic testing and slaughter evaluation were examined by use of multiple 
      linear regression. RESULTS: Pathogens that had a significant effect on any given 
      farm during any given year and the magnitude of that effect varied. However, at 
      16 and 24 weeks of age, a higher antibody titer was consistently associated with 
      a lower ADG. Mean differences in ADG between seropositive and seronegative pigs 
      were 18 g/d (0.04 lb/d) for SIV, 40 g/d (0.09 lb/d) for PRRSV, 38 g/d (0.08 lb/d) 
      for M hyopneumoniae, and 116 g/d (0.26 lb/d) for TGEV. Of the evaluations 
      performed at slaughter, only detection of lung lesions was consistently 
      associated with a decrease in ADG. CONCLUSIONS AND CLINICAL RELEVANCE: Results 
      suggest that subclinical infection with any of a variety of pathogens commonly 
      found in swine herds was associated with a decrease in ADG. Serologic testing was 
      more effective than slaughter evaluation in assessing the impact of subclinical 
      infection on ADG in these pigs.
FAU - Regula, G
AU  - Regula G
AD  - Department of Veterinary Pathobiology, College of Veterinary Medicine, University 
      of Illinois, Urbana 61802, USA.
FAU - Lichtensteiger, C A
AU  - Lichtensteiger CA
FAU - Mateus-Pinilla, N E
AU  - Mateus-Pinilla NE
FAU - Scherba, G
AU  - Scherba G
FAU - Miller, G Y
AU  - Miller GY
FAU - Weigel, R M
AU  - Weigel RM
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Am Vet Med Assoc
JT  - Journal of the American Veterinary Medical Association
JID - 7503067
RN  - 0 (Antibodies, Bacterial)
RN  - 0 (Antibodies, Viral)
SB  - IM
MH  - Actinobacillus Infections/blood/*physiopathology
MH  - Actinobacillus pleuropneumoniae/isolation & purification/pathogenicity
MH  - Animals
MH  - Antibodies, Bacterial/blood
MH  - Antibodies, Viral/blood
MH  - Cohort Studies
MH  - Female
MH  - Gastroenteritis, Transmissible, of Swine/blood/*physiopathology
MH  - Herpesvirus 1, Suid/isolation & purification/pathogenicity
MH  - Influenza A virus/isolation & purification/pathogenicity
MH  - Liver/pathology
MH  - Lung/pathology
MH  - Multivariate Analysis
MH  - Orthomyxoviridae Infections/blood/*physiopathology
MH  - Porcine Reproductive and Respiratory Syndrome/blood/*physiopathology
MH  - Porcine respiratory and reproductive syndrome virus/isolation & 
      purification/pathogenicity
MH  - Pseudorabies/blood/*physiopathology
MH  - Regression Analysis
MH  - Skin/pathology
MH  - Swine/*growth & development
MH  - Swine Diseases/*microbiology/virology
MH  - Transmissible gastroenteritis virus/isolation & purification/pathogenicity
MH  - Weight Gain
EDAT- 2000/09/21 11:00
MHDA- 2001/02/28 10:01
CRDT- 2000/09/21 11:00
PHST- 2000/09/21 11:00 [pubmed]
PHST- 2001/02/28 10:01 [medline]
PHST- 2000/09/21 11:00 [entrez]
AID - 10.2460/javma.2000.217.888 [doi]
PST - ppublish
SO  - J Am Vet Med Assoc. 2000 Sep 15;217(6):888-95. doi: 10.2460/javma.2000.217.888.