PMID- 11001315
OWN - NLM
STAT- MEDLINE
DCOM- 20010208
LR  - 20131121
IS  - 0173-0835 (Print)
IS  - 0173-0835 (Linking)
VI  - 21
IP  - 14
DP  - 2000 Aug
TI  - Analysis of acyclovir by high performance capillary electrophoresis with 
      on-column amperometric detection.
PG  - 2995-8
AB  - The separation of acyclovir (ACV) by high performance capillary electrophoresis 
      (HPCE) with on-column amperometric detection using 
      alpha-amino-5-mercapto-3,4-dithiazole (AMD) as internal standard is described. 
      The calibration line was linear in the range of 0.5-20 mg/L of ACV. The detection 
      limit was 0.15 mg/L of ACV. Its recovery ranged from 98 to 101% with relative 
      standard deviations (RSDs) from 1.9 to 3.2% (n = 5). This method was successfully 
      used for determining ACV in some pharmaceuticals and human urine. Comparable 
      results with HPCE with ultraviolet (UV) detection and amperometric detection were 
      obtained.
FAU - Zhang, S
AU  - Zhang S
AD  - Center of Instrumental Analysis and Chemistry Department, Zhengzhou University, 
      P.R. China. zhangshusheng@371.net
FAU - Yuan, Z
AU  - Yuan Z
FAU - Liu, H
AU  - Liu H
FAU - Zou, H
AU  - Zou H
FAU - Xiong, H
AU  - Xiong H
FAU - Wu, Y
AU  - Wu Y
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Germany
TA  - Electrophoresis
JT  - Electrophoresis
JID - 8204476
RN  - 0 (Antiviral Agents)
RN  - X4HES1O11F (Acyclovir)
SB  - IM
MH  - Acyclovir/*analysis/*isolation & purification
MH  - Antiviral Agents/*analysis/*isolation & purification
MH  - Electrophoresis, Capillary/methods
MH  - Humans
EDAT- 2000/09/23 11:00
MHDA- 2001/03/03 10:01
CRDT- 2000/09/23 11:00
PHST- 2000/09/23 11:00 [pubmed]
PHST- 2001/03/03 10:01 [medline]
PHST- 2000/09/23 11:00 [entrez]
AID - 10.1002/1522-2683(20000801)21:14<2995::AID-ELPS2995>3.0.CO;2-P [pii]
AID - 10.1002/1522-2683(20000801)21:14<2995::AID-ELPS2995>3.0.CO;2-P [doi]
PST - ppublish
SO  - Electrophoresis. 2000 Aug;21(14):2995-8. doi: 
      10.1002/1522-2683(20000801)21:14<2995::AID-ELPS2995>3.0.CO;2-P.