PMID- 11005119
OWN - NLM
STAT- MEDLINE
DCOM- 20010111
LR  - 20161124
IS  - 0960-7692 (Print)
IS  - 0960-7692 (Linking)
VI  - 15
IP  - 6
DP  - 2000 Jun
TI  - Automated cardiac output measurements by ultrasound are inaccurate at high 
      cardiac outputs.
PG  - 508-12
AB  - OBJECTIVE: The sonographic technique of automated cardiac output measurement 
      (ACM) is a promising new method to measure cardiac output and could be of use in 
      a high-risk obstetric unit in the treatment of pre-eclamptic patients. The aim 
      was to determine the accuracy of the ACM method. DESIGN: Comparative study of the 
      sonographic technique of ACM versus cardiac output measured by thermodilution 
      (TD). METHODS: The study included 39 intensive care patients, 21 men, 13 
      non-pregnant women and five severely pre-eclamptic pregnant patients, with a wide 
      range of cardiac outputs, in whom TD catheters had been inserted for clinical 
      reasons. Two separate experienced observers, blinded to the results obtained with 
      the other method, performed four successive measurements in each patient with 
      either the ACM or TD technique. The averaged cardiac output value per patient and 
      method was used for comparison. RESULTS: Cardiac output was successfully measured 
      with ACM and TD in 85 and 100% of patients, respectively. Mean cardiac output 
      measured by ACM (6.77 +/- 1.90 L/min) was significantly lower than that measured 
      by TD (9.12 +/- 3.06 L/min). Although cardiac output values obtained with ACM 
      were significantly correlated with those measured by TD, the ACM values were 
      consistently lower than TD values in the higher cardiac output range; the 
      relationship was represented by ACM = 0.35 TD + 3.55 L/min (r = 0.57, P < 0.001). 
      The (ACM - TD) difference increased significantly with cardiac output, through a 
      difference in stroke volume, not in heart rate. CONCLUSION: The ACM is not an 
      accurate tool to measure cardiac output in patients with a high cardiac output, 
      including treated pre-eclamptic women.
FAU - Basdogan, F
AU  - Basdogan F
AD  - Department of Obstetrics and Gynecology, Academic Hospital, Rotterdam, The 
      Netherlands.
FAU - Visser, W
AU  - Visser W
FAU - Struijk, P C
AU  - Struijk PC
FAU - Jansen, J R
AU  - Jansen JR
FAU - Vletter, W B
AU  - Vletter WB
FAU - Wladimiroff, J W
AU  - Wladimiroff JW
FAU - Lotgering, F K
AU  - Lotgering FK
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - England
TA  - Ultrasound Obstet Gynecol
JT  - Ultrasound in obstetrics & gynecology : the official journal of the International 
      Society of Ultrasound in Obstetrics and Gynecology
JID - 9108340
SB  - IM
MH  - Adult
MH  - Aged
MH  - Analysis of Variance
MH  - *Cardiac Output
MH  - Cardiac Output, High/*diagnostic imaging/physiopathology
MH  - Echocardiography, Doppler, Color/instrumentation/*methods/statistics & numerical 
      data
MH  - Electrocardiography
MH  - Female
MH  - Humans
MH  - Linear Models
MH  - Male
MH  - Middle Aged
MH  - Pre-Eclampsia/diagnostic imaging/physiopathology
MH  - Pregnancy
MH  - Reproducibility of Results
MH  - Thermodilution/instrumentation/methods/statistics & numerical data
EDAT- 2000/09/27 11:00
MHDA- 2001/02/28 10:01
CRDT- 2000/09/27 11:00
PHST- 2000/09/27 11:00 [pubmed]
PHST- 2001/02/28 10:01 [medline]
PHST- 2000/09/27 11:00 [entrez]
AID - 10.1046/j.1469-0705.2000.00128.x [doi]
PST - ppublish
SO  - Ultrasound Obstet Gynecol. 2000 Jun;15(6):508-12. doi: 
      10.1046/j.1469-0705.2000.00128.x.