PMID- 11025430 OWN - NLM STAT- MEDLINE DCOM- 20001227 LR - 20171101 IS - 0042-1138 (Print) IS - 0042-1138 (Linking) VI - 65 IP - 2 DP - 2000 TI - Transurethral microwave thermotherapy for symptomatic benign prostatic hyperplasia: short-term experience with Prostcare. PG - 89-94 AB - PURPOSE: To assess our short-term experience with transurethral microwave thermotherapy (TUMT) for symptomatic benign prostatic hyperplasia (BPH). PATIENTS AND METHODS: From August 1993 through July 1994, in total 65 patients with symptomatic BPH were enrolled into this study. The patients' ages ranged from 56 to 95 years with a mean of 70 years. Under local anesthesia with intraurethral instillation of Xylocaine jelly only, all patients received one session of TUMT for up to 60 min with Prostcare equipment. Uroflowmetry was performed and international prostatic symptom score (IPSS) determined before 3 and 6 months after TUMT for assessment of efficacy. All adverse events were recorded and evaluated for clinical relevance. RESULTS: At 3 and 6 months following TUMT, the mean IPSS decreased from 19.7 +/- 6.8 (baseline) to 12.8 +/- 8.2 (-46%) and to 15.5 +/- 9.0 (-21%), respectively; the maximal urine flow rate at 3 and 6 months increased from 9.1 +/- 4.8 ml/s (baseline) to 11.0 +/- 4.9 ml/s (+21%) and to 10.9 +/- 5.6 ml/s (+19%), respectively. During TUMT, burning sensation was the most frequent complaint (38.5%), followed by urethral discomfort (29.2%) and urgency (9.2%). Two patients (3.1%) interrupted TUMT, because of intolerable pain. Following TUMT micturition pain (73.8%) and gross hematuria (45.9%) were the most adverse events. Most of these adverse events disappeared within 2 weeks. One patient suffered from skin erosion over the penoscrotal junction 1 week later. None had retrograde ejaculation; 1 patient complained of erectile dysfunction. CONCLUSION: Although the efficacy of TUMT with Prostcare became less prominent 6 months after TUMT, TUMT was still a tolerable, safe alternative treatment of BPH, especially in patients who were not suitable for transurethral resection of the prostate or anesthesia. CI - Copyright 2000 S. Karger AG, Basel FAU - Tsai, Y S AU - Tsai YS AD - Department of Urology, National Cheng Kung University Hospital, Tainan, Taiwan. FAU - Lin, J S AU - Lin JS FAU - Tong, Y C AU - Tong YC FAU - Tzai, T S AU - Tzai TS FAU - Yang, W H AU - Yang WH FAU - Chang, C C AU - Chang CC FAU - Cheng, H L AU - Cheng HL FAU - Lin, Y M AU - Lin YM FAU - Jou, Y C AU - Jou YC LA - eng PT - Clinical Trial PT - Journal Article PL - Switzerland TA - Urol Int JT - Urologia internationalis JID - 0417373 SB - IM MH - Aged MH - Aged, 80 and over MH - *Diathermy/methods MH - Humans MH - Male MH - Microwaves/*therapeutic use MH - Middle Aged MH - Prostatic Hyperplasia/physiopathology/*therapy MH - Time Factors MH - Urethra MH - Urodynamics EDAT- 2000/10/12 11:00 MHDA- 2001/02/28 10:01 CRDT- 2000/10/12 11:00 PHST- 2000/10/12 11:00 [pubmed] PHST- 2001/02/28 10:01 [medline] PHST- 2000/10/12 11:00 [entrez] AID - 64846 [pii] AID - 10.1159/000064846 [doi] PST - ppublish SO - Urol Int. 2000;65(2):89-94. doi: 10.1159/000064846.