PMID- 11027911 OWN - NLM STAT- MEDLINE DCOM- 20001214 LR - 20190915 IS - 0885-3924 (Print) IS - 0885-3924 (Linking) VI - 20 IP - 4 DP - 2000 Oct TI - Course of symptoms and quality of life measurement in Complex Regional Pain Syndrome: a pilot survey. PG - 286-92 AB - Few data have been published regarding the natural history, course of symptoms, and quality of life in Complex Regional Pain Syndrome (CRPS). To obtain preliminary data regarding these important issues in CRPS, a set of patient self-report questionnaires were mailed to patients with the diagnosis of CRPS who had been assessed and/or treated at a tertiary university-based pain center in the United States. Self-reports of demographic information, symptoms, the Neuropathic Pain Scale, and a modified Brief Pain Inventory (mBPI) were received from 31 CRPS patients. Approximately 75% of patients reported initial symptoms of pain, swelling, coldness, and color changes. An additional 71% had weakness and inability to move the extremity as initial symptoms. Weakness at some time during their course of CRPS was described by 97%. A majority reported no overall improvement or worsening of symptoms over time (mean 3.3 years). The pain descriptors with the highest mean values were "deep" (6.4/10), "unpleasant" (6.4), "sensitive" (5.7), "surface" (5.4), and "dull" (5.3) pains. Significant sleep disturbance was reported by 80%. CRPS had a severe impact on quality of life, with substantial interference reported in 9 of 10 mBPI activity items by a majority of these patients. These findings should be viewed with caution and should not be generalized to the entire CRPS population because the cohort was small and select. A large multicenter prospective study needs to be performed to validate these preliminary findings. FAU - Galer, B S AU - Galer BS AD - Department of Pain Medicine and Palliative Care, Beth Israel Medical Center, New York, NY 10003, USA. FAU - Henderson, J AU - Henderson J FAU - Perander, J AU - Perander J FAU - Jensen, M P AU - Jensen MP LA - eng PT - Journal Article PL - United States TA - J Pain Symptom Manage JT - Journal of pain and symptom management JID - 8605836 SB - IM MH - Adult MH - Complex Regional Pain Syndromes/*diagnosis/epidemiology/*psychology MH - Demography MH - Disease Progression MH - Female MH - Functional Laterality/physiology MH - Humans MH - Hypokinesia/etiology MH - Immobilization/physiology MH - Male MH - Pain Measurement/psychology/statistics & numerical data MH - Pilot Projects MH - Psychophysiology/statistics & numerical data MH - Quality of Life/*psychology MH - Sleep Wake Disorders/etiology/psychology MH - Stress, Physiological/complications EDAT- 2000/10/12 11:00 MHDA- 2001/02/28 10:01 CRDT- 2000/10/12 11:00 PHST- 2000/10/12 11:00 [pubmed] PHST- 2001/02/28 10:01 [medline] PHST- 2000/10/12 11:00 [entrez] AID - S0885-3924(00)00183-4 [pii] AID - 10.1016/s0885-3924(00)00183-4 [doi] PST - ppublish SO - J Pain Symptom Manage. 2000 Oct;20(4):286-92. doi: 10.1016/s0885-3924(00)00183-4.